Results 61 to 70 of about 6,278 (255)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Cajuína e cristalina: as transformações espaciais vistas pelos cronistas que atuaram nos jornais de Teresina entre 1950 e 1970

open access: yesRevista Brasileira de História, 2007
Este artigo reflete sobre Teresina (PI), nos meados do século XX, período em que essa capital, num movimento similar ao ocorrido em outras cidades do mesmo porte, passou por múltiplas e variadas intervenções arquitetônicas e espaciais.
Francisco Alcides do Nascimento
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

EURASIAN CHRONICLE

open access: yesЕвразийская интеграция: экономика, право, политика, 2021
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openaire   +9 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Realidad, crónica y opinión: los avatares del viaje de Anna de Austria a España (1570) a través de fuentes mixtas

open access: yesMélanges de la Casa de Velázquez, 2013
Philip II’s fourth wife, his niece Anne of Austria, embarked on a long and complicated journey from Prague to Madrid, which lasted a total of five months—from 4 May 1570, the day of her wedding by proxy, until 26 November, the date of her public entrance
Esther Borrego Gutiérrez
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Reflection of the Turkic epic tradition in the chronicle image of Prince Svyatoslav Igorevich

open access: yesЗолотоордынское обозрение
Research objectives: To examine elements of the Turkic epic tradition in the chronicle image of Prince Svyatoslav Igorevich. Research materials: Historiographic sources, Russian chronicles, historical works, Turkic epics.
Aksanov A.V., Kozlov S.A.
doaj   +1 more source

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