Results 71 to 80 of about 471,273 (365)

The Mitochondrial Guardian α‐Amyrin Mitigates Alzheimer's Disease Pathology via Modulation of the DLK‐SARM1‐ULK1 Axis

Advanced Science, EarlyView.
Dietary habits play a key role in chronic diseases, and higher annual consumption of fruit and vegetable may lower risk of dementia. Artificial intelligence predicts the lipid‐like compound α‐Amyrin (αA) from plants with edible peels as a drug candidate against Alzheimer's disease.
Shu‐Qin Cao, Juan Ignacio Jiménez‐Loygorri, Yunguang Qiu, You Jung Kang, Khanh Van Do, Annabel E. Smith, Junjie Huang, Jun‐ping Pan, Lipeng Mao, Ang Li, Hangge Yang, Yahyah Aman, Maria Jose Donate Lagartos, Sofie Hindkjær Lautrup, Anbin Chen, Kristina Xiao Liang, Hailong Zhang, Juan Yi, Xurui Jin, Tin Cho Cheung, Olympia Apokotou, Florentia Papastefanaki, Rebecca Matsas, William A. McEwan, Feixiong Cheng, Hansang Cho, Guobing Chen, Huanxing Su, Konstantinos Palikaras, Oscar Junhong Luo, Qian Hua Zhao, Ding Ding, Cornelia van Duijn, Nektarios Tavernarakis, Patricia Boya, Tewin Tencomnao, Evandro F. Fang   +36 more
wiley   +1 more source

The boundary of the chronology violating set

, 2016
A sufficiently general definition for the future and past boundaries of the chronology violating region is given. In comparison to previous studies, this work does not assume that the complement of the chronology violating set is globally hyperbolic. The
Minguzzi, E.
core   +1 more source

The WAIS Divide deep ice core WD2014 chronology – Part 1: Methane synchronization (68–31 ka BP) and the gas age–ice age difference

, 2014
. The West Antarctic Ice Sheet Divide (WAIS Divide, WD) ice core is a newly drilled, high-accumulation deep ice core that provides Antarctic climate records of the past ∼68 ka at unprecedented temporal resolution.
C. Buizert, K. Cuffey, J. Severinghaus, D. Baggenstos, T. Fudge, E. Steig, Bradley R. Markle, M. Winstrup, R. Rhodes, E. Brook, T. Sowers, G. Clow, Haiwen Cheng, R. Edwards, M. Sigl, J. McConnell, K. Taylor   +16 more
semanticscholar   +1 more source

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

THE RELATIONSHIP BETWEEN SOLAR AND VOLCANIC ACTIVITY AND THE CHRONOLOGY OF ARCHAEOLOGICAL CULTURES OF EURASIA IN THE 4TH–1ST MILLENNIA BC

Journal of Ancient History and Archaeology
A well-known problem of archaeological chronology is that radiocarbon chronology differs from historical chronology. Historical chronology of the Bronze Age corresponds to dendrochronology and radiocarbon chronology in case of using Bayesian statistics ...
Stanislav GRIGORIEV
doaj   +1 more source

Chronology protection in stationary three-dimensional spacetimes

, 2011
We study chronology protection in stationary, rotationally symmetric spacetimes in 2+1 dimensional gravity, focusing especially on the case of negative cosmological constant.
A Campoleoni, A Dabholkar, BS Kay, C Herdeiro, D Freedman, EK Boyda, GS Hall, J Brown, J Raeymaekers, J Raeymaekers, Joris Raeymaekers, K Gödel, L Dyson, M Bañados, M Caldarelli, M Lubo, M Mars, M Rooman, MM Caldarelli, MS Costa, N Drukker, R Bousso, S Deser, S Hawking, V Balasubramanian, WJ Stockum van   +25 more
core   +2 more sources

The Antarctic ice core chronology (AICC2012): an optimized multi-parameter and multi-site dating approach for the last 120 thousand years

, 2012
. The deep polar ice cores provide reference records commonly employed in global correlation of past climate events. However, temporal divergences reaching up to several thousand years (ka) exist between ice cores over the last climatic cycle.
D. Veres, L. Bazin, A. Landais, H. T. M. Kele, B. Lemieux-Dudon, F. Parrenin, P. Martinerie, E. Blayo, T. Blunier, E. Capron, J. Chappellaz, S. Rasmussen, M. Severi, A. Svensson, B. Vinther, E. Wolff   +15 more
semanticscholar   +1 more source

Dead Matter, Living Machines: Repurposing Crustaceans' Abdomen Exoskeleton for Bio‐Hybrid Robots

Advanced Science, EarlyView.
Crustacean exoskeletons, repurposed from food waste, are engineered into sustainable bending actuators combining biotic structure with synthetic control. The augmented exoskeletons achieve rapid and robust motion with lightweight body and can be used as part of robotic manipulators, grippers and swimmers.
Sareum Kim, Kieran Gilday, Josie Hughes
wiley   +1 more source

Impacts of storm chronology on the morphological changes of the Formby beach and dune system, UK

, 2015
. Impacts of storm chronology within a storm cluster on beach/dune erosion are investigated by applying the state-of-the-art numerical model XBeach to the Sefton coast, northwest England.
P. Dissanayake, Jennifer Brown, H. Karunarathna   +2 more
semanticscholar   +1 more source

Direct Observation of Electric‐Field‐Driven Phase Transitions Associated with Energy Storage in Antiferroelectric Films

Advanced Science, EarlyView.
The electric‐field‐driven antiferroelectric‐to‐ferroelectric phase transition in epitaxial PbZrO3 films is directly visualized by in situ aberration‐corrected scanning transmission electron microscopy. A sequential transition pathway involving an orthorhombic ferrielectric phase and a monoclinic ferroelectric phase, ultimately stabilizing into a ...
Yan‐Peng Feng, Mei‐Xiong Zhu, Ru‐Jian Jiang, Yu‐Jia Wang, Yun‐Long Tang, Yin‐Lian Zhu, Xiu‐Liang Ma   +6 more
wiley   +1 more source