Formulation of Chrysomycin A Cream for the Treatment of Skin Infections [PDF]
Molecules, 2022 Chrysomycin A, a compound derived from marine microorganisms, proved to have a specific great in vitro inhibitory effect on methicillin-resistant Staphylococcus aureus (MRSA).
Xuanrong Sun +2 more
exaly +4 more sources
Chrysomycin A Regulates Proliferation and Apoptosis of Neuroglioma Cells via the Akt/GSK-3β Signaling Pathway In Vivo and In Vitro [PDF]
Marine Drugs, 2023 Glioblastoma (GBM) is a major type of primary brain tumor without ideal prognosis and it is therefore necessary to develop a novel compound possessing therapeutic effects.
Huawei Zhang +2 more
exaly +4 more sources
Chrysomycin A Inhibits the Proliferation, Migration and Invasion of U251 and U87-MG Glioblastoma Cells to Exert Its Anti-Cancer Effects [PDF]
Molecules, 2022 Chrysomycin A (Chr-A), an antibiotic from Streptomyces, is reported to have anti-tumor and anti-tuberculous activities, but its anti-glioblastoma activity and possible mechanism are not clear. Therefore, the current study was to investigate the mechanism
Huawei Zhang +2 more
exaly +4 more sources
Chrysomycin A Reshapes Metabolism and Increases Oxidative Stress to Hinder Glioblastoma Progression [PDF]
Marine DrugsGlioblastoma represents the predominant and a highly aggressive primary neoplasm of the central nervous system that has an abnormal metabolism. Our previous study showed that chrysomycin A (Chr-A) curbed glioblastoma progression in vitro and in vivo ...
Huawei Zhang +2 more
exaly +4 more sources
Chrysomycin A Derivatives for the Treatment of Multi-Drug-Resistant Tuberculosis [PDF]
ACS Central Science, 2020 Xiaoguang Lei +2 more
exaly +3 more sources
Comprehensive Genomic Analysis of Marine Strain Streptomyces sp. 891, an Excellent Producer of Chrysomycin A with Therapeutic Potential [PDF]
Marine Drugs, 2022 Chrysomycin A is one of the most promising therapeutic candidates for treating infections caused by multidrug-resistant Gram-positive bacteria. By hybridizing next-step generation (Illumina) and third-generation (PacBio) sequencing technologies, a high ...
Xu Hu +6 more
doaj +2 more sources
Comparative Transcriptome Analysis of Two Chrysomycin-Producing Wild-Type and Mutant Strains of Streptomyces sp. 891 [PDF]
Metabolites, 2022 Chrysomycin A (CA), a promising antibiotic agent, usually coexists with two analog chrysomycins B (CB) and C (CC) produced by several wild-type (WT) Streptomyces strains.
Wangjie Zhu +5 more
doaj +2 more sources
Mechanochemical preparation of chrysomycin A self-micelle solid dispersion with improved solubility and enhanced oral bioavailability [PDF]
Journal of Nanobiotechnology, 2021 Background Chrysomycin A (CA) has been reported as numerous excellent biological activities, such as antineoplastic and antibacterial. Though, poor solubility of CA limited its application in medical field.
Zhuomin Xu +11 more
doaj +2 more sources
Chrysomycins, Anti-Tuberculosis C-Glycoside Polyketides from Streptomyces sp. MS751 [PDF]
Marine DrugsA new dimeric C-glycoside polyketide chrysomycin F (1), along with four new monomeric compounds, chrysomycins G (2), H (3), I (4), J (5), as well as three known analogues, chrysomycins A (6), B (7), and C (8), were isolated and characterised from a ...
Jiaming Yu +15 more
doaj +2 more sources
Diversity, antimicrobial and herbicidal activities of actinomycetes and fungi from Hermetia illucens [PDF]
BMC MicrobiologyActinomycetes and fungi have been found to be important sources of bioactive natural products. Evaluation the diversity of culturable insect-asscociated microorganisms, and screening strains with bioactive activity holds a promising for the development ...
Mengru Liu +8 more
doaj +2 more sources