Results 71 to 80 of about 20,290 (242)

Engineered Living Systems With Self‐Organizing Neural Networks: From Anatomy to Behavior and Gene Expression

Advanced Science, EarlyView.
Ectodermal tissue excised from Xenopus embryos self‐organizes into a three‐dimensional mucociliary organoid. Here, we generate a neural variant, termed neurobot, by implanting neural precursor cells. Neurobots develop mature neurons, adopt distinct morphologies, exhibit more complex motility, and respond differentially to neuroactive compounds. Imaging
Haleh Fotowat, Laurie O'Neill, Léo Pio‐Lopez, Megan M. Sperry, Patrick Erickson, Tiffany Lin, Michael Levin   +6 more
wiley   +1 more source

A Novel Function of Nonadecanoic Acid in Regulating Glucose Homeostasis

Advanced Science, EarlyView.
This study identifies the odd‐chain fatty acid C19:0 as an endogenous ligand of GPR120 that promotes glucose homeostasis via Gαq signaling. In obesity, elevated palmitic acid suppresses endogenous C19:0 production through a miRNA–PPARα–HACL1 pathway, offering a promising direction for understanding the role of OCFAs in human health.
Yanting Hou, Yinghua Ma, Qin Liu, Dingling Ma, Yuxin Tong, Lili Xu, Xiaolong Chu, Jingzhou Wang, Maodi Liang, Mengyuan Zhao, Huizi Zhang, Yurui Su, Jianxin Xie, Cuizhe Wang, Jun Zhang   +14 more
wiley   +1 more source

Using Deficit Functions for Crew Planning in Aviation

Transport and Telecommunication, 2017
We use deficit functions (DFs) to decompose an aviation schedule of aircraft flights into a minimal number of periodic and balanced chains (flight sequences).
Gertsbakh Ilya B., Stern Helman I.
doaj   +1 more source

Hierarchical Summary Statistics Encoding Across Primary Visual and Posterior Parietal Cortices

Advanced Science, EarlyView.
This study shows that mouse V1 simultaneously encodes the ensemble mean and variance of motion, providing a robust summary‐statistic representation that persists despite single‐neuron variability. These signals propagate to PPC, where they are transformed into abstract category representations during decision making.
Young‐Beom Lee, Oliver James, Gaeun Jung, Doyun Lee, Yee‐Joon Kim   +4 more
wiley   +1 more source

Adversarial Robustness of Deep Learning-Based Malware Detectors via (De)Randomized Smoothing

IEEE Access
Deep learning-based malware detectors have been shown to be susceptible to adversarial malware examples, i.e. malware examples that have been deliberately manipulated in order to avoid detection.
Daniel Gibert, Giulio Zizzo, Quan Le, Jordi Planes   +3 more
doaj   +1 more source

Semantic chunking

, 2020
Long sentences pose a challenge for natural language processing (NLP) applications. They are associated with a complex information structure leading to increased requirements for processing resources. Although the issue is present in many areas of research, there is little uniformity in the solutions used by research communities dedicated to individual
openaire   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

An Analysis of Lexical Chunks in “Mina 1” and “Let\'s Learn Persian 1” Textbooks: A Comparative Study Based on Lewis Model and Their Degree of Fixedness [In Persian]

زبان کاوی کاربردی
The acquisition of vocabulary is a critical component in language instruction. One effective approach to language learning is the study of lexical chunks, which are combinations of words that form a single conceptual unit and are ingrained in the ...
Maryam Ghasemian, Nasser Rashidi
doaj  

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Context-Aware Retrieval Augmented Generation Using Similarity Validation to Handle Context Inconsistencies in Large Language Models

IEEE Access
Large Language Models (LLMs) have transformed natural language processing by offering human-like responses. However, issues such as incorrect information (hallucinations) and errors in specific subject areas remain, especially in Retrieval Augmented ...
Enrico Collini, Felix Indra Kurniadi, Paolo Nesi, Gianni Pantaleo   +3 more
doaj   +1 more source