Results 131 to 140 of about 660 (227)

Social ties in old age: the effect of the COVID-19 pandemic. [PDF]

open access: yesEur J Ageing
Menashe-Oren A, Uccheddu D, Rizzi EL.
europepmc   +1 more source

Lilrb4a Suppression Reprograms Microglia to Mitigate APOE4‐Associated Amyloid Plaques and Cerebral Amyloid Angiopathy in Association With a PPAR‐Linked Pro‐Clearance State

open access: yesAdvanced Science, EarlyView.
Targeting Lilrb4a in Apolipoprotein E4 (APOE4)‐associated Alzheimer's disease (AD) reprograms microglia toward a beneficial, phagocytic state. Genetic deletion or antisense inhibition of Lilrb4a suppresses p‐SHP2/NF‐κB/STAT1 signaling, restores PPAR‐linked lipid and energy metabolism, and reduces amyloid plaque burden and cerebral amyloid angiopathy ...
Changxu Nie   +12 more
wiley   +1 more source

Single‐Particle Mid‐Infrared Photothermal Imaging Reveals Hidden Heterogeneity in Real‐World Micro‐ and Nanoplastics

open access: yesAdvanced Science, EarlyView.
Mid‐infrared photothermal imaging enables multidimensional profiling of micro‐ and nanoplastics in bottled water. A total of 9.9 × 104 particles L−1 is detected, with 64% in the nanoscale regime. Spectral evolution, including peak narrowing and band shifts, reveals local chain reorganization in polyethylene terephthalate (PET), highlighting intrinsic ...
Xinyu Deng   +4 more
wiley   +1 more source

Meta-Analysis of Bioaccessibility of Hydrophobic Compounds in Buttermilk Matrices: A Systematic Review and Quantitative Synthesis. [PDF]

open access: yesMolecules
Sagandyk A   +6 more
europepmc   +1 more source

A Computational Strategy for Identifying Self‐Assembling Food‐Derived Molecules for Antiparasitic Nanotherapy

open access: yesAdvanced Science, EarlyView.
An integrated computational screening strategy identified ursolic acid (UA) and 18β‐glycyrrhetinic acid (18βGA) as a self‐assembling food‐derived molecular pair. The resulting carrier‐free nanoparticles (UA‐18βGA) showed synergistic antiparasitic activity, reduced combined toxicity, and host‐protective anti‐inflammatory effects in zebrafish and murine ...
Shenye Qu   +8 more
wiley   +1 more source

Churning losses and efficiency in gearboxes [Elektronisk resurs]

open access: yes, 2014
Efficient transmissions systems are key to producing competitive motor vehicles that have a smaller environmental impact. Gears are the main components in vehicle transmissions and although they are already highly efficient, there is still room for ...
Björklund, Stefan,   +4 more
core  

Friend, Not Foe: Lowered Tissue Reactivity to Long‐Term Polyimide Implants

open access: yesAdvanced Science, EarlyView.
The choice of optimal neural probe designs remains a major challenge in the field of neurotechnology. This study investigated the biocompatibility of several probe variations, including material, thickness, width, and implantation strategy. It highlights the clear advantage of soft polyimide probes over stiff silicon probes for better device ...
Corinne Orlemann   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy