Results 191 to 200 of about 23,834 (285)

Integrating Spatial Proteogenomics in Cancer Research

open access: yesAdvanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang   +13 more
wiley   +1 more source

Leaky‐Integrate‐Fire Neuron via Synthetic Antiferromagnetic Coupling and Spin‐Orbit Torque

open access: yesAdvanced Science, EarlyView.
A spintronic leaky‐integrate‐and‐fire neuron is realized using Spin Orbit Torque driven domain‐wall motion for integration and synthetic antiferromagnetic coupling for the leaky process. The specialized Hall‐bar geometry enables controlled DW dynamics, achieving repeatable integration and firing events. This compact, CMOS‐compatible design highlights a
Badsha Sekh   +8 more
wiley   +1 more source

PIK3CA Mutations Downregulate PPT1 to Promote Adipogenesis by Suppressing P300 Depalmitoylation and Phase Separation

open access: yesAdvanced Science, EarlyView.
This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen   +7 more
wiley   +1 more source

Electrochemical Nitrate Reduction Reaction to Ammonia at Industrial‐Level Current Densities

open access: yesAdvanced Science, EarlyView.
This review starts from the mechanism and theoretical basis of electrochemical nitrate reduction reaction (NO3−RR), and systematically summarizes and discusses the design strategies of industrial‐level current density catalysts. In addition, the progress of industrial‐level NO3−RR‐based electrolyzers, including flow reactor and membrane electrode ...
Zhijie Cui   +4 more
wiley   +1 more source

Interface Engineering Strategies for Realizing Anode‐Free Sodium Batteries: A Review

open access: yesAdvanced Energy Materials, EarlyView.
This review examines anode‐free sodium batteries as a promising solution for advancing sodium‐based energy storage. It focuses on the role of interface engineering in addressing challenges such as sodium deposition, interface stability, and dendrite growth.
Yulian Dong   +6 more
wiley   +1 more source

Decoding Short‐Range Order in Amorphous Two‐Dimensional Nanosheets for Efficient and Durable Ampere‐Level Seawater Electrolysis: A Case Study of Amorphous Ni(OH)2

open access: yesAdvanced Energy Materials, EarlyView.
This work uncovers the atomic‐scale origins of exceptional HER performance in amorphous Ni(OH)2 nanosheets by combining atom probe tomography, DFT simulations, and operando spectroscopy. We identify distinct short‐range‐order motifs that accelerate water dissociation, proton transport, and hydrogen adsorption. Embedding Pt single atoms further enhances
Xin Geng   +4 more
wiley   +1 more source

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