Results 231 to 240 of about 1,332,942 (289)

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

Advanced Materials, EarlyView.
This work explores the MOF landscape to select a single, optimal candidate for successfully delivering cancer drugs (gemcitabine, paclitaxel, SN‐38) into tough pancreatic tumors. Machine learning and simulations guide this search, demonstrating colloidal stability, excellent biocompatibility, cellular uptake, and sustained release.
Francesca Melle, Dhruv Menon, João Conniot, Jon Ostolaza‐Paraiso, Sergio Mercado, Jhenifer Oliveira, Xu Chen, Bárbara B. Mendes, João Conde, David Fairen‐Jimenez   +9 more
wiley   +1 more source

An immune challenge affects growth dynamics, oxidative stress and survival in wild spotless starling nestlings. [PDF]

J Exp Biol
Parejo-Pulido D, Casquero S, Romero-Haro AÁ, Pérez-Rodríguez L.   +3 more
europepmc   +1 more source

State‐of‐the‐Art, Insights, and Perspectives for MOFs‐Nanocomposites and MOF‐Derived (Nano)Materials

Advanced Materials, EarlyView.
Different approaches to MOF‐NP composite formation, such as ship‐in‐a‐bottle, bottle‐around‐the‐ship and in situ one‐step synthesis, are used. Owing to synergistic effects, the advantageous features of the components of the composites are beneficially combined, and their individual drawbacks are mitigated.
Stefanos Mourdikoudis, Subhajit Dutta, Saqib Kamal, Sergio Gómez‐Graña, Isabel Pastoriza‐Santos, Stefan Wuttke, Lakshminarayana Polavarapu   +6 more
wiley   +1 more source

Positive perceptions of brown bears linked to long-term cohabitation in the Iberian Peninsula. [PDF]

Sci Rep
Severino P, Graça M, Negrões N, Barros T, Carvalho J, Ferreira E, Hartasánchez R, Malheiro B, Rosalino LM, Torres RT, Glikman JA.   +10 more
europepmc   +1 more source

Resumos Tema III - Bem-estar animal e refinamento para uma ciência de alta qualidade

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2014
openaire   +2 more sources

Thermal Processing Creates Water‐Stable PEDOT:PSS Films for Bioelectronics

Advanced Materials, Volume 37, Issue 13, April 2, 2025.
Instead of using chemical cross–linkers, it is shown that PEDOT:PSS thin films for bioelectronics become water‐stable after a simple heat treatment. The heat treatment is compatible with a range of rigid and elastomeric substrates and films are stable in vivo for >20 days.
Siddharth Doshi, Margaux O. A. Forner, Pingyu Wang, Salim El Hadwe, Amy T. Jin, Gerwin Dijk, Kenneth Brinson, Juhwan Lim, Antonio Dominguez‐Alfaro, Carina Yi Jing Lim, Alberto Salleo, Damiano G. Barone, Guosong Hong, Mark L. Brongersma, Nicholas A. Melosh, George G. Malliaras, Scott T. Keene   +16 more
wiley   +1 more source

A ciência política na atualidade

, 1994
Céli Regina Jardim Pinto
openalex   +2 more sources

Bi‐Functional Topospecific Nanoparticles to Promote Immune‐Tumor Cell Engagement as A New Immunotherapeutic Strategy

Advanced Materials, EarlyView.
A Janus‐engineered nanoplatform (J‐pHLIP‐PD1), featuring separate tumor‐ and immune‐targeting faces, bridges melanoma cells and cytotoxic T lymphocytes using toposelective pHLIP and anti‐PD‐1 presentation. This strategy elicits robust antitumor responses, promotes immunogenic tumor cell death, suppresses lung metastasis in vivo, and provides a modular,
Alba Ortuño‐Bernal, Sandra Clara‐Trujillo, Elena Lucena‐Sánchez, Francisco J. Hicke, Andrea Escudero, Sandra Pradana‐López, Nelia Jiménez‐Alduan, Paula Díez, Alba García‐Fernández, Ramón Martínez‐Máñez   +9 more
wiley   +1 more source

Giant Fully Fused Tetrapodal Rylenimides: Design, Synthesis and Optoelectrochemical Characterization via Alkyl Chain and Core Engineering Strategies. [PDF]

Org Lett
Alonso-Navarro MJ, Suárez-Blas F, Martínez JI, Ramos MM, Segura JL.   +4 more
europepmc   +1 more source

Resumos Theme IV - Redução e substituição do uso de animais na ciência e indústria

Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2014
openaire   +2 more sources