Results 41 to 50 of about 27,201 (172)

A Sequence‐Based Update on Amino Acid Substitutions in Influenza Polymerase Acidic Protein in Europe That Alter Baloxavir Susceptibility From 2009 to 2025

Influenza and Other Respiratory Viruses, Volume 20, Issue 7, July 2026.
ABSTRACT Background Influenza causes 650,000 deaths, 3–5 million hospitalizations, and 1 billion cases worldwide each year. There is a limited repertoire of antivirals available to tackle this burden, highlighting the risk of developing resistance to current drugs.
Alejandro Martín‐Toribio, Inés Inchausti‐Moya, Marina Toquero‐Asensio, Sonia García‐Díaz, Javier Sanchez‐Martinez, Carla Rodriguez‐Crespo, Silvia Galindo‐Carretero, Raquel Iglesia‐Aparicio, Celia Lopez‐Gonzalo, Ana Antón‐Contreras, Silvia Rojo‐Rello, Marta Dominguez‐Gil, Marta Hernández, Jose M. Eiros, Estanislao Nistal‐Villan, Iván Sanz‐Muñoz   +15 more
wiley   +1 more source

Ciências Farmacêuticas

, 2015
Ciências ...
Kelly Gianezini, Organizadoras, S. Valvassori, Samira   +1 more
core  

Synthesis of Novel C‐Acyl‐Glycosyl Sulfonamides via Pd‐Catalyzed Carbonylative Coupling

European Journal of Organic Chemistry, Volume 29, Issue 23, 16 June 2026.
A Pd‐catalyzed carbonylative coupling of 1‐iodo‐glycals with diverse sulfonamides using Mo(CO)6 enables efficient access to C‐acyl‐glycosyl sulfonamides.This robust and versatile strategy delivers novel glycoside derivatives in good to excellent yields, highlighting their potential for drug discovery.
João A. F. Silva, Mônica F. Z. J. Toledo, Flávia Manarin, João H. de Araujo‐Neto, Milene M. Hornink, Hélio A. Stefani   +5 more
wiley   +1 more source

Atitudes em relação à Bioestatística de discentes e docentes da Faculdade de Ciências Farmacêuticas de Araraquara-UNESP

, 2010
In this study, the attitudes of students and teachers at the Faculty of Pharmaceutical Sciences of Araraquara (UNESP University) towards Biostatistics were assessed.
Bonafé, F. S S, Loffredo, L. C M, Campos, Juliana Alvares Duarte Bonini   +2 more
core  

ISOLAMENTO E IDENTIFICAÇÃO DE MICOBACTÉRIAS EM ÁGUAS TRATADAS PROVENIENTES DO SISTEMA DE ABASTECIMENTO DE ARARAQUARA-SP

Alimentos e Nutrição, 2012
A qualidade da água é muito importante para a saúde e bem-estar do ser humano e o sistema de abastecimento público deve fornecer água de qualidade e em quantidade suficiente para toda a população.
Josiane Aparecida GASPAR-GRILLO, Adalberto FARACHE FILHO, Adolfo Carlos Barreto SANTOS, Clarice Queico Fujimura LEITE   +3 more
doaj  

Mapping Functionally Relevant Tractable Lysines of Challenging Protein Targets by Covalent Fragment Screening

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Screening a lysine‐targeting covalent fragment library against challenging protein targets revealed suitable warheads and characterized binding sites for the development of targeted covalent ligands. Covalent fragment screening has become an established strategy for identifying targetable amino acid residues or viable chemical starting points against ...
Noémi Csorba, Péter Ábrányi‐Balogh, Zoltán Orgován, Tibor Viktor Szalai, György G. Ferenczy, Levente Kollár, Nikolett Péczka, Tímea Imre, József Simon, Pál Szabó, Gitta Schlosser, Martina Hrast, Stanislav Gobec, Varbina Ivanova, Carles Galdeano, Aleksandra Kopranovic, Marc Neumann, Franz‐Josef Meyer‐Almes, György Miklós Keserű   +18 more
wiley   +1 more source

X Congresso Iberoamericano de Ciências Farmacêuticas - Nota de Abertura

, 2023
X Congresso Iberoamericano de Ciências Farmacêuticas - Nota de ...
Ramos, Fernando
core  

Avaliação da atividade hepatoprotetora do asiaticosídeo em modelo experimental de lesão hepática por paracetamol em ratos

Revista de Ciências Farmacêuticas Básica e Aplicada, 2014
O asiaticosídeo é um triterpenóide presente no extrato da Centella asiatica, sendo responsável pela atividade terapêutica desta planta em doenças hepáticas crônicas.
Gustavo Henrique da Silva, Pedro Paulo Barros, Gisele Mara Silva Gonçalves, Eder Adnan de Jesus   +3 more
doaj  

Molecular Insights and Repellent Efficacy of the Essential Oil and Major Compounds From Piper cyrtopodon (Miq.) C.DC (Piperaceae) Against Aedes aegypti (Linnaeus, 1762) (Culicidae)

Archiv der Pharmazie, Volume 359, Issue 6, June 2026.
The essential oil and major compounds from Piper cyrtopodon exhibit potent, long‐lasting repellent activity against Aedes aegypti mosquitoes, combined with low cytotoxicity and favorable molecular docking interactions with odorant‐binding proteins. These findings highlight its potential for the development of alternative products for bite prevention ...
Maria L. L. da Costa, Renata G. de Azevedo, Sergio M. Nunomura, Rita de C. S. Nunomura, Gemilson S. Pontes, Rosemary A. Roque, Tatiane P. de Souza, André C. de Oliveira   +7 more
wiley   +1 more source

MiR‐21‐5p Protects Embryonic Growth and Heart Function During Developmental Hypoxia by Dampening HIF Responses and Altering Gene Expression

Comprehensive Physiology, Volume 16, Issue 3, June 2026.
miR‐21‐5p protects embryonic growth and heart function during developmental hypoxia by dampening HIF responses and shifting gene networks toward improved cardiomyocyte survival and calcium handling. This work identifies miR‐21‐5p as a promising therapeutic target for preventing fetal growth restriction and cardiovascular impairment in high‐risk ...
Bernardo J. Krause, Ximena Calle, Ranya V. Kumar, Youguo Niu, Oriana Ramirez‐Herrera, Damariz Gonzalez, Barbara Bernal, Sage G. Ford, Rachael C. Crew, Anna L. K. Cochrane, German A. Arenas, Alex Di Genova, Dino A. Giussani   +12 more
wiley   +1 more source