Results 31 to 40 of about 528,483 (278)

Detrimental incorporation of excess Cenp-A/Cid and Cenp-C into Drosophila centromeres is prevented by limiting amounts of the bridging factor Cal1 [PDF]

, 2010
Propagation of centromere identity during cell cycle progression in higher eukaryotes depends critically on the faithful incorporation of a centromere-specific histone H3 variant encoded by CENPA in humans and cid in Drosophila.
Ahmad, Allshire, Bischof, Blower, Camahort, Cheeseman, Cohen, Collins, Dalal, Dunleavy, Edgar, Erhardt, Fitzgerald-Hayes, Foltz, Fujita, Furuyama, Furuyama, Gassmann, Goshima, Hayashi, Heeger, Heun, Hori, Jansen, Joglekar, Joglekar, Jäger, Jäger, Lam, Maddox, Maiato, Meluh, Meraldi, Metaxakis, Mizuguchi, Moreno-Moreno, Okada, Pandey, Parks, Perpelescu, Pidoux, Przewloka, Santaguida, Schittenhelm, Schittenhelm, Schuh, Sonnichsen, Sugimoto, Sun, Takahashi, Talbert, Thibault, Torras-Llort, Trazzi, Vagnarelli, Van Hooser, Williams, Winey, Yang   +58 more
core   +1 more source

Color-Induced Displacement double stars in SDSS

, 2004
We report the first successful application of the astrometric color-induced displacement technique (CID, the displacement of the photocenter between different bandpasses due to a varying contribution of differently colored components to the total light),
Bailey, Christy, D. Pourbaix, Finlator, Fukugita, G. R. Knapp, Gunn, Gunn, Gunn, Harris, Heintz, Hogg, Høg, Ivezic, Ivezic, J. E. Gunn, Juric, Pier, Pourbaix, R. H. Lupton, Richards, Skrutskie, Smith, Sorokin, Wielen, York, Ž. Ivezić   +26 more
core   +1 more source

The effects of Non3 mutations on chromatin organization in Drosophila melanogaster

Вавиловский журнал генетики и селекции
The nucleolus is a large membraneless subnuclear structure, the main function of which is ribosome biogenesis. However, there is growing evidence that the function of the nucleolus extends beyond this process.
A. A. Yushkova, A. A. Ogienko, E. N. Andreyeva, A. N. Pindyurin, A. E. Letiagina, E. S. Omelina   +5 more
doaj   +1 more source

Whole-genome sequencing for national surveillance of Shiga toxin–producing Escherichia coli O157 [PDF]

, 2015
Background. National surveillance of gastrointestinal pathogens, such as Shiga toxin–producing Escherichia coli O157 (STEC O157), is key to rapidly identifying linked cases in the distributed food network to facilitate public health interventions.
Adak, Goutam, Ashton, Philip M., Byrne, Lisa, Cowley, Lauren A, Dallman, Timothy J, Ellis, Richard J, Elson, Richard, Grant, Kathie, Green, Jonathan, Hanage, William P, Jenkins, Claire, Perry, Neil T, Petrovska, Liljana, Underwood, Anthony, Wain, John   +14 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Plasma damage in floating metal-insulator-metal capacitors [PDF]

, 2001
In this paper, charging induced damage (CID) to metal-insulator-metal capacitors (MIMCs), is reported. CID does not necessarily lead to direct yield loss, but may also induce latent damage leading to reliability losses.
Ackaert, Jan, Coppens, P., De Backer, E., Wang, Zhichun   +3 more
core   +2 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Indacaterol/glycopyrronium versus salmeterol/fluticasone in the prevention of clinically important deterioration in COPD: results from the FLAME study

Respiratory Research, 2018
Background Chronic obstructive pulmonary disease (COPD) is a progressive disease and a composite endpoint could be an indicator of treatment effect on disease worsening.
Antonio R. Anzueto, Konstantinos Kostikas, Karen Mezzi, Steven Shen, Michael Larbig, Francesco Patalano, Robert Fogel, Donald Banerji, Jadwiga A. Wedzicha   +8 more
doaj   +1 more source

Sarilumab in Polyarticular‐Course Juvenile Idiopathic Arthritis: Dose‐Finding and One‐Year Analysis of a Phase 2b, Open‐Label, Multicenter Study

Arthritis Care &Research, Accepted Article.
Objective This study assessed sarilumab in treating patients with polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods This phase 2b, open‐label study (NCT02776735) consisted of three sequential parts (each with a core‐treatment and extension‐phase). During part 1, three doses were assessed in two weight groups (Group A/B: ≥30–60 kg/≥10–<
Fabrizio De Benedetti, Inmaculada C. Penadés, Irina Nikishina, Ivan Foeldvari, Alberto J. Spindler, Anna Kozlova, Nadina Rubio‐Pérez, Pierre Quartier, Zbigniew Żuber, Raul Barria, Daniel Clemente, Gabriel V. Cornejo, Katherine Marzan, Nancy Liu, Christine Xu, Stephen DiMartino, Angeliki Giannelou, Fei Cao‐Ghoul, Bolanle Akinlade, Lydie Baret‐Cormel   +19 more
wiley   +1 more source

Anomalias congênitas na perspectiva da vigilância em saúde: compilação de uma lista com base na CID-10

Epidemiologia e Serviços de Saúde, 2020
Resumo Objetivo: Propor uma lista de anomalias congênitas com códigos correspondentes na Classificação Estatística Internacional de Doenças e Problemas Relacionados à Saúde – 10ᵃ Revisão (CID-10), visando a aplicação no âmbito da vigilância em saúde ...
João Matheus Bremm, Augusto César Cardoso-dos-Santos, Vivyanne Santiago Magalhães, Ana Cláudia Medeiros-de-Souza, Ronaldo Fernandes Santos Alves, Valdelaine Etelvina Miranda de Araujo, Eduardo Marques Macario, Wanderson Kleber de Oliveira, Lavínia Schüler-Faccini, Maria Teresa Vieira Sanseverino, Giovanny Vinícius Araújo de França   +10 more
doaj   +2 more sources