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Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

Arthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez +295 more
wiley +1 more source

Sistema embebido software-hardware para transformación de señales de video analógico en tiempo real

Serie Científica de la Universidad de las Ciencias Informáticas
La persistencia de sistemas basados en video analógico para aplicaciones industriales y de vigilancia hace necesario la capacidad de integrar información gráfica adicional en estas señales. La digitalización completa para su procesamiento representa una
Jorge Humberto Vázquez Leiva +3 more
doaj

Optimization and identification of bound polyphenols from rice bean (Vigna umbellata) skin dietary fiber, antioxidant activities and α-glucosidase inhibition mechanism

Food Chemistry: X
Vigna umbellata is an important homologous medicinal and food legume, and its fruit is rich in polyphenols. Acidic, alkaline (highest yield) and enzymatic methods were used to release bound polyphenols from rice bean skin dietary fiber. 44 compounds were
Jing Liang +8 more
doaj +1 more source

Real‐Life Study on Gilteritinib‐Related Infections (GilteRInf): An Italian SEIFEM Study

American Journal of Hematology, EarlyView.
Elisa Buzzatti +25 more
wiley +1 more source

Pharmacokinetics, effectiveness and safety of certolizumab pegol in children and adolescents with active juvenile idiopathic arthritis: 9+‐year results from a multicenter, open‐label study

Arthritis &Rheumatology, Accepted Article.
Objective To assess the pharmacokinetics, effectiveness, safety, and immunogenicity of certolizumab pegol (CZP) in polyarticular‐course juvenile idiopathic arthritis (pcJIA). Methods Pediatric Arthritis Study of Certolizumab Pegol (NCT01550003), a multicenter, open‐label study, enrolled patients 2–17 years with active pcJIA and inadequate response ...
Hermine I Brunner +28 more
wiley +1 more source

Autoria coletiva, autoria ontológica e intertextualidade: aspectos conceituais e tecnológicos

Ciência da Informação, 2008
A autoria não está restrita ao texto — literário, científico, técnico, jornalístico —, mas a qualquer tipo de criação humana, com suas peculiaridades e problemáticas próprias.
Antonio Lisboa de Carvalho Miranda +2 more
doaj

‘They Even Have the Capacity, but the Places Aren't Prepared to Receive Them’: Community Environment and Participation of Autistic Children in a Family‐Engaged Research Analysis

Autism Research, EarlyView.
ABSTRACT To examine the associations between community environmental barriers and support and the participation of autistic children, and to interpret these findings from the perspective of caregivers engaged as research partners. This cross‐sectional observational study employed a mixed‐methods design.
Léia Cordeiro de Oliveira +7 more
wiley +1 more source

Pharmacometric evaluation of pre‐referral rectal artesunate in children with severe malaria

British Journal of Clinical Pharmacology, EarlyView.
Aims Parenteral artesunate is the preferred first‐line treatment for severe malaria. Pre‐referral rectal artesunate suppositories are recommended where parenteral treatment is inaccessible. In this study, we compared dihydroartemisinin exposure and model‐predicted early parasite clearance following rectal artesunate and intravenous artesunate in ...
Ayorinde Adehin +6 more
wiley +1 more source

Accumulation patterns of flavonoids and phenolic acids in different colored sweet potato flesh revealed based on untargeted metabolomics

Food Chemistry: X
Sweet potatoes are rich in flavonoids and phenolic acids, showing incomparable nutritional and health value. In this investigation, we comprehensively analyzed the secondary metabolite profiles in the flesh of different-colored sweet potato flesh.
Xiaolin Wan +4 more
doaj +1 more source

A Century of Learning: The Story of ESA's Education Committee, 1918–2025

The Bulletin of the Ecological Society of America, EarlyView.
Abstract The Education Committee and its precursors have been highly influential within the Ecological Society of America. Here we document the Education Committee's history, from its origins in reviewing curricular materials through major contributions to ecological literacy, teaching innovation, diversity initiatives, and professional development ...
Kenneth M. Klemow +6 more
wiley +1 more source

medicine