Results 111 to 120 of about 508,149 (238)

Desarrollo de la comprensión lectora a través de la colaboración y el diálogo

open access: yesInvestigaciones Sobre Lectura
La comprensión lectora profunda y crítica es un instrumento necesario para el desarrollo de una ciudadanía plena. Es de una gran complejidad dado que involucra diferentes habilidades y procesos, donde los y las docentes han de asumir el rol de ...
Ana Cristina Blasco-Serrano   +2 more
doaj   +1 more source

Structural and functional dissection of the WH2/DAD motif of INF2, a formin linked to human inherited degenerative disorders

open access: yesThe FEBS Journal, Volume 293, Issue 3, Page 825-841, February 2026.
The INF2 WH2/DAD domain, composed of hydrophobic and basic regions, forms a single α‐helix in solution. The hydrophobic segment is essential for INF2 function, as its deletion disrupts actin dynamics and causes nuclear abnormalities, like those seen in pathogenic INF2 DID variants. In contrast, natural INF2 WH2/DAD variants found in patients with renal
Leticia Labat‐de‐Hoz   +5 more
wiley   +1 more source

Pleiotrophin/Midkine Pathway Is Dysregulated in a TDP‐43A315T Mouse Model of Amyotrophic Lateral Sclerosis (ALS)

open access: yesNeuropathology, Volume 46, Issue 1, February 2026.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a fatal motor neuron disease (MND) characterized by progressive degeneration of both upper and lower motor neurons, along with skeletal muscles innervated by them. The identification of key molecules involved in disease pathology remains crucial for ALS, as no curative treatment is currently available ...
Paloma Martínez‐Alesón   +3 more
wiley   +1 more source

Institucionalizar la función de investigación en la formación docente

open access: yesEducación, Formación e Investigación, 2015
El propósito del presente artículo es contribuir a la discusión sobre el desarrollo de la función de investigación en el sistema formador. En primer lugar, se presenta un breve análisis de las principales políticas implementadas por el Estado nacional ...
Inés Cappellacci   +5 more
doaj  

CYP1A2 Genotype and the Ergogenic Effect of Acute Caffeine Intake on Muscular Strength and Endurance Performance in Trained Individuals

open access: yesScandinavian Journal of Medicine &Science in Sports, Volume 36, Issue 2, February 2026.
ABSTRACT This study examined whether CYP1A2 (rs762551) genotype modulates the acute ergogenic effects of caffeine on muscular strength and endurance performance in resistance‐trained men and women. Ninety‐four resistance‐trained participants (47 females, 47 males; 39 AA, 44 AC, 11 CC) completed a randomized, triple‐blind, placebo‐controlled, crossover ...
Juan Jesús Montalvo‐Alonso   +5 more
wiley   +1 more source

Las ciencias de la complejidad y la educación médica

open access: diamond, 2017
Alberto Lifshitz Guinzberg   +1 more
openalex   +1 more source

Unsymmetrical β‐Fused Blatter Radical Zinc Phthalocyanines

open access: yesChemistry – A European Journal, Volume 32, Issue 4, 23 January 2026.
Herein, we report the first synthesis of a new class of β‐fused Blatter–Zn phthalocyanines featuring a persistent radical π‐system, π–π‐driven crystal packing, and SOMO‐centered redox behavior. Single‐crystal X‐ray diffraction shows packing motifs dominated by centrosymmetric π‐π dimers.
Adrián Hernández   +9 more
wiley   +1 more source

Sind i‐Motiv‐Strukturen in DNA kompatibel mit Cytosin–Ag(I)–Cytosin‐Basenpaaren?

open access: yesAngewandte Chemie, Volume 138, Issue 2, 9 January 2026.
Ein i‐Motiv/Duplex‐Konjugat wurde hinsichtlich seiner Fähigkeit untersucht, die Protonen der hemiprotonierten C:CH+‐Basenpaare durch AgI‐Ionen zu ersetzen, um C–AgI–C‐Basenpaare zu bilden. Interessanterweise wird nur ein einziges solches Basenpaar gebildet, bevor sich das Oligonukleotid in eine Duplexstruktur umlagert.
Victoria Seiffert   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy