Protein Repeats from First Principles [PDF]
Some natural proteins display recurrent structural patterns. Despite being highly similar at the tertiary structure level, repeating patterns within a single repeat protein can be extremely variable at the sequence level. We use a mathematical definition
Becher, Veronica Andrea +4 more
core +1 more source
Genetics and genomic medicine in Argentina [PDF]
A historical summary of genetics and genomic medicine in Argentina. We go through the achievements and difficulties in the implementation of genetic and genomic services both in academia and health care.Fil: Vishnopolska, Sebastián Alexis.
Avena +27 more
core +1 more source
Genes of different catabolic pathways are coordinately regulated by Dal81 in Saccharomyces cerevisiae [PDF]
Yeast can use a wide variety of nitrogen compounds. However, the ability to synthesize enzymes and permeases for catabolism of poor nitrogen sources is limited in the presence of a rich one.
Bermudez Moretti, Mariana +2 more
core +3 more sources
Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA [PDF]
The checkpoint kinases Chk1 and ATR are broadly known for their role in the response to the accumulation of damaged DNA. Because Chk1 activation requires its phosphorylation by ATR, it is expected that ATR or Chk1 down-regulation should cause similar ...
Federico, Maria Belén +4 more
core +1 more source
Prostate tumor growth is impaired by CtBP1 depletion in high-fat diet-fed mice [PDF]
Clinical and epidemiologic data suggest that obesity is associated with more aggressive forms of prostate cancer, poor prognosis, and increased mortality.
Cotignola, Javier Hernan +11 more
core +1 more source
VIP contribution to the decidualization program: regulatory T cell recruitment [PDF]
During early pregnancy, the human uterus undergoes profound tissue remodeling characterized by leukocyte invasion and production of proinflammatory cytokines, followed by tissue repair and tolerance maintenance induction.
Agüero, Mariana +5 more
core +1 more source
Progeny performance and pathogen attack relative to elevation in a neotropical tree [PDF]
Climate and resource availability at the parent tree location are known to explain progeny characteristics; however, few studies have examined the role of resistance or tolerance to pathogens, even though climate is a main driver of pathogen abundance ...
Bergero, Hernán +7 more
core +3 more sources
Sobre la enseñanza de las ciencias naturales
En el presente trabajo se describen diversas posiciones sobre el currículo de ciencias naturales haciendo particular énfasis en la manera como se ha venido construyendo el saber científico y su apropiación escolar a través de la llamada alfabetización ...
José Antonio Chamizo, Yosajandi Pérez
doaj +1 more source
Insect insights: case studies using 3D-printed specimen models as a tool for accessibility, education and outreach in a Natural History Museum [PDF]
Insects are the most diverse but least appreciated animals, and Natural History Museums are vital for communicating their ecological importance. Entomological drawers display insect variety, but their power to engage is limited by the format of mounted ...
Adrián Sánchez Albert +8 more
doaj +3 more sources
Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor [PDF]
Glucocorticoids are essential for life, but are also implicated in disease pathogenesis and may produce unwanted effects when given in high doses.
Alvarez, Lautaro Damian +14 more
core +3 more sources

