Results 11 to 20 of about 855,400 (214)

Protein Repeats from First Principles [PDF]

open access: yes, 2016
Some natural proteins display recurrent structural patterns. Despite being highly similar at the tertiary structure level, repeating patterns within a single repeat protein can be extremely variable at the sequence level. We use a mathematical definition
Becher, Veronica Andrea   +4 more
core   +1 more source

Genetics and genomic medicine in Argentina [PDF]

open access: yes, 2018
A historical summary of genetics and genomic medicine in Argentina. We go through the achievements and difficulties in the implementation of genetic and genomic services both in academia and health care.Fil: Vishnopolska, Sebastián Alexis.
Avena   +27 more
core   +1 more source

Genes of different catabolic pathways are coordinately regulated by Dal81 in Saccharomyces cerevisiae [PDF]

open access: yes, 2015
Yeast can use a wide variety of nitrogen compounds. However, the ability to synthesize enzymes and permeases for catabolism of poor nitrogen sources is limited in the presence of a rich one.
Bermudez Moretti, Mariana   +2 more
core   +3 more sources

Kinase-independent function of checkpoint kinase 1 (Chk1) in the replication of damaged DNA [PDF]

open access: yes, 2012
The checkpoint kinases Chk1 and ATR are broadly known for their role in the response to the accumulation of damaged DNA. Because Chk1 activation requires its phosphorylation by ATR, it is expected that ATR or Chk1 down-regulation should cause similar ...
Federico, Maria Belén   +4 more
core   +1 more source

Prostate tumor growth is impaired by CtBP1 depletion in high-fat diet-fed mice [PDF]

open access: yes, 2014
Clinical and epidemiologic data suggest that obesity is associated with more aggressive forms of prostate cancer, poor prognosis, and increased mortality.
Cotignola, Javier Hernan   +11 more
core   +1 more source

VIP contribution to the decidualization program: regulatory T cell recruitment [PDF]

open access: yes, 2014
During early pregnancy, the human uterus undergoes profound tissue remodeling characterized by leukocyte invasion and production of proinflammatory cytokines, followed by tissue repair and tolerance maintenance induction.
Agüero, Mariana   +5 more
core   +1 more source

Progeny performance and pathogen attack relative to elevation in a neotropical tree [PDF]

open access: yes, 2019
Climate and resource availability at the parent tree location are known to explain progeny characteristics; however, few studies have examined the role of resistance or tolerance to pathogens, even though climate is a main driver of pathogen abundance ...
Bergero, Hernán   +7 more
core   +3 more sources

Sobre la enseñanza de las ciencias naturales

open access: yesRevista Iberoamericana de Educación, 2017
En el presente trabajo se describen diversas posiciones sobre el currículo de ciencias naturales haciendo particular énfasis en la manera como se ha venido construyendo el saber científico y su apropiación escolar a través de la llamada alfabetización ...
José Antonio Chamizo, Yosajandi Pérez
doaj   +1 more source

Insect insights: case studies using 3D-printed specimen models as a tool for accessibility, education and outreach in a Natural History Museum [PDF]

open access: yesNatural History Collections and Museomics
Insects are the most diverse but least appreciated animals, and Natural History Museums are vital for communicating their ecological importance. Entomological drawers display insect variety, but their power to engage is limited by the format of mounted ...
Adrián Sánchez Albert   +8 more
doaj   +3 more sources

Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor [PDF]

open access: yes, 2014
Glucocorticoids are essential for life, but are also implicated in disease pathogenesis and may produce unwanted effects when given in high doses.
Alvarez, Lautaro Damian   +14 more
core   +3 more sources

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