Results 201 to 210 of about 48,283 (264)

Effect of COMT and UGT1A Variants on Clinical Response to Opicapone in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) is the second most common neurodegenerative disease. Symptomatic treatment is based on dopaminergic replacement. With disease progression, the initial benefit of levodopa becomes inconsistent, and motor complications emerge.
Elena Ojeda‐Lepe, Sergio García‐Díaz, Laura Muñoz‐Delgado, Miguel Martín‐Bórnez, Silvia Jesús, Dolores Buiza‐Rueda, Marta Bonilla‐Toribio, Rafael Díaz‐Belloso, Daniel Macías‐García, Astrid Adarmes‐Gómez, Antonio Luque‐Ambrosiani, Rocío Pineda‐Sánchez, Lorena Clavijo‐Jiménez, Fátima Carrillo‐García, Pilar Gómez‐Garre, Pablo Mir   +15 more
wiley   +1 more source

Authoritarianism in youth social life: systematic literature review (2015-2025). [PDF]

Front Psychol
Troncoso-Tejada G, Polanco-Levicán K, Gálvez-Nieto JL, Ortiz-Velosa E, González Casas D.   +4 more
europepmc   +1 more source

R&D Organization and Corporate Social Responsibility Specialization

Managerial and Decision Economics, EarlyView.
ABSTRACT In this paper, we examine whether the scope of corporate social responsibility (CSR) should be broad or narrow. A broad scope covers both production and R&D investment decisions, while a narrow scope applies only to production decisions. We show that both firms' choices and the government's preferences depend on the level of CSR concern and on
Quan Dong, Juan Carlos Bárcena‐Ruiz, Amagoia Sagasta   +2 more
wiley   +1 more source

[Primary care in the face of the obesity and diabetes epidemic: An integrated and preventive challenge]. [PDF]

Aten Primaria
Lagrú Romero T, Machado Pérez CL.
europepmc   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Bilateral strength balance of knee extensor and flexor muscles in female soccer players. [PDF]

Front Physiol
Andrades-Ramírez O, Ulloa-Díaz D, Romero-Vera L, Alfaro-Castillo B, Muñoz-Bustos G, Jorquera-Aguilera C, Carvajal-Parodi C, Chirosa-Ríos LJ.   +7 more
europepmc   +1 more source

Interdiction Models and Heuristics for Graph Propagation

Networks, EarlyView.
ABSTRACT Given a graph G=(V,E)$$ G=\left(V,E\right) $$ and a set S⊂V$$ S\subset V $$ of activated/infected nodes, we consider the problem of determining the set of c$$ c $$ nodes that minimizes the network propagation on the subgraph that results from the removal of those c$$ c $$ nodes. To measure network propagation, we assume that a node i$$ i $$ is
Agostinho Agra, José Maria Samuco
wiley   +1 more source

Ethical Decision-Making in Chilean University Students: Behavioral and Electroencephalographic Evidence from Professional Ethical Dilemmas. [PDF]

Behav Sci (Basel)
Vergara-Morales J, Matamala B, Retamal B, Gantiva C.   +3 more
europepmc   +1 more source

The Uncharted Territory of the New Obesity Drugs in Users Without Obesity: A Sociomedical Perspective

Obesity, EarlyView.
ABSTRACT The off‐label use of glucagon‐like peptide‐1 receptor agonists (GLP‐1ra) among people without obesity and/or diabetes is rapidly expanding, despite a lack of clinical justification or safety data in this population. This Perspective explores the sociomedical dimensions of this trend, highlighting key research gaps and emerging hypotheses ...
Fernanda Baeza Scagliusi, Bruno Gualano, Pernille Andreassen, Cindi SturtzSreetharan, Sissel Due Jensen, Alexandra Brewis   +5 more
wiley   +1 more source

[Association between technology addiction and academic performance in Latin American university students in 2024] [PDF]

Rev Fac Cien Med Univ Nac Cordoba
Real Delor RE, Mendoza Melgar JG, Gomes da Silva Neto P, Oliveira Silva Gomes CB, Nascimento de Medeiros G, Pimenta Cavalcante L.   +5 more
europepmc   +1 more source