Results 191 to 200 of about 282,596 (287)

Chronic Exposure to Cigarette Smoke Induces Pyroptosis in Pulmonary Epithelial Cells via EGR1/USP44/TRAF6 Axis in COPD. [PDF]

J Inflamm Res
Cao C, Zhong Z, Wu B, Zou B, Jia H, Xu J, Xiao G, Xia S.   +7 more
europepmc   +1 more source

Intestinal host-microbe interactions fuel pulmonary inflammation in cigarette smoke exposed mice. [PDF]

Gut Microbes
Yang-Jensen SK, Näegele N, Sonne SB, Koeninger L, Pineault M, Tremblay F, Kristensen NN, Bay L, Aubin S, Morissette MC, Jensen BAH.   +10 more
europepmc   +1 more source

Maximising Participation in the Australian National Lung Cancer Screening Program: A Discrete Choice Experiment of Eligible, High‐Risk Individuals

Respirology, EarlyView.
A discrete choice experiment of lung cancer screening attributes. Study results demonstrate that lung cancer screening uptake could be significantly increased by offering program navigators and personalised invitations. The findings contribute significant insights to inform future improvements to the design and implementation of the Australian National
Peiwen Jiang, Caitlin Paton, Richard Norman, Marianne Weber, Henry M. Marshall, Fraser Brims, Kuan Pim Lim, Sarah York, Georgia Bartlett, Richard De Abreu Lourenco, Nicole M. Rankin   +10 more
wiley   +1 more source

Epigenetic Dysregulation of the NKX2‐1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

Respirology, EarlyView.
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota, Keiko Kan‐o, Yumiko Ishii, Tomoaki Koga, Takeshi Sawada, Kei‐ichiro Yasunaga, Shingo Usuki, Tatsuya Katsuno, Shigesato Inoue, Tomohiro Ogawa, Akihiro Jo, Satoru Fukuyama, Mitsuyoshi Nakao, Hiroaki Ogata, Mizuho A. Kido, Sachiko Tsukita, Koichiro Matsumoto, Isamu Okamoto   +17 more
wiley   +1 more source

Genetic resilience to chronic obstructive pulmonary disease is a clinically distinct subtype in individuals with cigarette smoke exposure. [PDF]

Respir Res
Ghosh AJ, Chang KY, Moll M, Hess J, Coyne LP, Panda S, Cho MH, Bowler RP, Glatt SJ, Hersh CP.   +9 more
europepmc   +1 more source

Illicit Drug‐Derived Volatile Organic Compounds as Markers for Application in Noncontact Detection Technology

The Chemical Record, EarlyView.
This review highlights the characteristic odor markers of illicit drugs, emphasizing volatile markers from both natural and synthetic sources, and explores the shift from canine‐based detection to emerging noncontact sensing technologies. Illicit drug use remains a global concern, requiring effective detection methods to counter evolving concealment ...
Minwoo Kim, Solpa Lee, Anmo J. Kim, Cong Wang, Yongwoo Jang   +4 more
wiley   +1 more source

Cigarette Smoke Extract-Induced Necroptosis Causes Mitochondrial DNA Release and Inflammation of Bronchial Epithelial Cells. [PDF]

Int J Chron Obstruct Pulmon Dis
Mizumura K, Ozoe R, Nemoto Y, Furusho N, Kurosawa Y, Kozu Y, Oki T, Maruoka S, Gon Y.   +8 more
europepmc   +1 more source

Effect of Stimulus Duration on the Electrogustometric Threshold

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Electrogustometry (EGM)—the psychophysical measurement of human taste function by the application of weak electric currents to taste bud fields—has proved useful in clinical and research settings. Although EGM detection thresholds have been reported to be sensitive to stimulus duration, studies differ on this point and have not been ...
Toshi Matsuda, Richard L. Doty
wiley   +1 more source

Cigarette smoke extract promotes metastasis and oxaliplatin resistance in colon adenocarcinoma through GDF15/ERBB2/AKT pathway. [PDF]

Eur J Med Res
Jiang W, Wang Y, Wang WJ, Zhou BC, Hu XS, Xu AM.   +5 more
europepmc   +1 more source