Results 81 to 90 of about 384,417 (265)

Introducing Two Novel Indices for Evaluating Coronary Artery Stenosis: Athero‐Inflammatory Index and Athero‐Inflammatory Glucose Index

Journal of Clinical Laboratory Analysis, EarlyView.
In this study, we introduced and investigated two novel indices named athero‐inflammatory (AI) index and athero‐inflammatory glucose (AIG) index with coronary stenosis among a total of 2326 participants (761 angiography (+), 406 angiography (−) and 1159 controls) in Mashhad. We found that AI index and AIG index were better and more reliable markers for
Rana Kolahi Ahari, Mohsen Moohebati, Mohammad Tajfard, Habibollah Esmaily, Gordon Ferns, Majid Ghayour‐Mobarhan, Sara Saffar Soflaei   +6 more
wiley   +1 more source

Who Knows Best What the Next Year Will Hold for You? The Validity of Direct and Personality‐based Predictions of Future Life Experiences Across Different Perceivers

European Journal of Personality, EarlyView., 2020
Abstract This study explored the validity of person judgements by targets and their acquaintances (‘informants’) in longitudinally predicting a broad range of psychologically meaningful life experiences. Judgements were gathered from four sources (targets, N = 189; and three types of informants, N = 1352), and their relative predictive validity was ...
Nele M. Wessels, Johannes Zimmermann, Daniel Leising, Jan‐Erik Lönnqvist   +3 more
wiley   +1 more source

Physiologically Based Pharmacokinetic (PBPK) Model to Predict the Magnitude of Drug–Drug Interaction Between Fezolinetant and CYP1A2 Inhibitors

The Journal of Clinical Pharmacology, EarlyView.
Abstract Fezolinetant is a non‐hormonal, selective neurokinin 3 receptor antagonist approved in multiple countries including the United States, in Europe, and in Asia for the treatment of moderate to severe vasomotor symptoms in menopausal women. Fezolinetant is primarily metabolized by CYP1A2 and was found to be a sensitive substrate for CYP1A2 ...
Mary P. Choules, Yukio Otsuka, Jace C. Nielsen, Megumi Iwai, Peter L. Bonate   +4 more
wiley   +1 more source

Electronic cigarettes and subsequent cigarette smoking in young people: A systematic review. [PDF]

Addiction
Abstract Aims To assess the evidence for a relationship between the use of e‐cigarettes and subsequent smoking in young people (≤29 years), and whether this differs by demographic characteristics. Methods Systematic review with association direction plots (searches to April 2023).
Begh R, Conde M, Fanshawe TR, Kneale D, Shahab L, Zhu S, Pesko M, Livingstone-Banks J, Lindson N, Rigotti NA, Tudor K, Kale D, Jackson SE, Rees K, Hartmann-Boyce J.   +14 more
europepmc   +2 more sources

Physiologically Based Pharmacokinetic Modeling to Predict Nicotine Pharmacokinetics of Nicotine Pouches Under Naturalistic Use Conditions

The Journal of Clinical Pharmacology, EarlyView.
Abstract Adult users of traditional tobacco products like combustible cigarettes (CC) or moist smokeless tobacco (MST) products can reduce exposure to toxicants by switching to potentially less harmful alternatives such as tobacco‐free nicotine pouches (NP). Nicotine exposure assessment is an important consideration to determine the switching potential
Ali Salehi, Mohamadi A. Sarkar, Jennifer H. Smith, Ali A. Rostami   +3 more
wiley   +1 more source

The Impact of Physician Intervention and Tobacco Control Policies on Average Daily Cigarette Consumption Among Adult Smokers [PDF]

Physicians' advice to stop smoking has been found to increase smoking cessation rates in controlled clinical trials. However, these finding may not be applicable under real world conditions.
John A. Tauras, Lan Liang
core  

Cigarette Smoking and Parkinson's Disease [PDF]

, 2007
This is a review on cigarette smoking and Parkinson's disease (PD). The relationship between cigarette smoking and Parkinson's disease is very controversial.
Das, Salil K., Miller, Leah R.
core  

Population Pharmacokinetics and Exposure–Response Relationships of Etrolizumab in Patients with Moderately‐to‐Severely Active Crohn's Disease

The Journal of Clinical Pharmacology, EarlyView.
Abstract This study aimed to characterize the pharmacokinetics (PK) of etrolizumab, an IgG1‐humanized monoclonal anti‐β7 integrin antibody, and assess its exposure–response (ER) relationship for key clinical outcomes in patients with moderately‐to‐severely active Crohn's disease.
Anita Moein, Jakob Ribbing, Moustafa M. A. Ibrahim, Wenhui Zhang, Nastya Kassir   +4 more
wiley   +1 more source

Study of Risk Factors and Image Findings of Isolated Abdominal Incidentally Detected Aortic Dissection

Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 429-435, March/April 2025.
We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi, Hidenori Onishi, Koji Maeno, Masaya Nakagaichi, Ikue Tsukushi, Youichi Kitano, Yoshitaka Makino, Hiroyuki Hayashi, Hidekazu Terasawa, Hiroko Kabuto, Toshihiro Misawa, Taku Sanada, Azusa Hisada, Kazuo Notsumata, Kazuhiro Okafuji, Osamu Yamamura   +15 more
wiley   +1 more source

Assessing a prediction model for depression risk using an early adolescent sample with self‐reported depression

JCPP Advances, EarlyView.
Abstract Background Major depressive disorder (MDD) in adolescence is a risk factor for poor physical and psychiatric outcomes in adulthood, with earlier age of onset associated with poorer outcomes. Identifying Depression Early in Adolescence Risk Score (IDEA‐RS) is a model for predicting MDD in youth aged >15 years, but replication in younger samples
Eileen Y. Xu, Niamh MacSweeney, Gladi Thng, Miruna C. Barbu, Xueyi Shen, Alex S. F. Kwong, Liana Romaniuk, Andrew McIntosh, Stephen M. Lawrie, Heather C. Whalley   +9 more
wiley   +1 more source