Results 201 to 210 of about 242,907 (315)

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Smart Carbon Dot Nanomaterials: Emerging Structure, Properties, and Biomedical Insights—A Comprehensive Review

MetalMat, EarlyView.
This review presents recent advances in smart carbon dot (CD) nanomaterials, emphasizing their synthesis, structural design, fluorescence mechanisms, and biomedical applications. CDs, typically below 10 nm, exhibit tunable photoluminescence, excellent stability, and biocompatibility.
Trisita Ghosh, Palash Das, Narayan Chandra Das   +2 more
wiley   +1 more source

Body Size, Dental Pathology, and Maternal Genetic Diversity of Ancient Horses in the Eastern Baltic Sea Region and Western Russia

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT The early evolutionary history of modern domestic horses (Equus caballus/Equus ferus caballus), known as the DOM2 lineage, is well documented due to numerous archaeological and ancient DNA (aDNA) studies. Although many uncertainties remain in the domestication timeline, current evidence suggests that the domestication of modern horses began in
Johanna Honka, Daniela Salazar, Arthur O. Askeyev, Igor V. Askeyev, Oleg V. Askeyev, Jouni Aspi, Gulshat Sh. Asylgaraeva, Markku Niskanen, Kristiina Mannermaa, Suvi Olli, Noora Piipponen, Giedrė Piličiauskienė, Dilyara N. Shaymuratova, Renat R. Valiev, Laura Kvist   +14 more
wiley   +1 more source

Transitions from cigarette smoking by geolocation among US adults: Results from waves 1-6 of the Population Assessment of Tobacco and Health (PATH) study 2013-2021. [PDF]

Tob Induc Dis
Ozga JE, Abadi MH, Jao NC, Kingsbury JH, Parks MJ, Tackett AP, Xie W, Xu S, Zhang J, Stanton CA.   +9 more
europepmc   +1 more source

Potential of Ginkgo biloba Extract to Intervene in Chronic Inflammation‐Related Diseases

Phytotherapy Research, EarlyView.
Chronic inflammation is a pathological mechanism underpinning many diseases. Ginkgo biloba extract (GBE) is well known for its anti‐inflammatory property. GBE and its active constituents have been shown to attenuate pro‐inflammatory cytokine production, suppress nuclear factor kappa B activation, restore redox homeostasis, and modulate disease‐relevant
Yipeng Lin, Inho Cho, Xue Zhu, Ke Wang, Ling Zhu, Wenchang Wong, Michael Murray, Fanfan Zhou   +7 more
wiley   +1 more source

Trends in vaping and smoking between 2018 and 2023-24: results from the Belgian Health Interview Survey. [PDF]

Eur J Public Health
Hermans L, Gisle L, Barhdadi S, Charafeddine R.   +3 more
europepmc   +1 more source

Smuggling Sovereignty: Trade, Transgression, and State Authority

Economic Anthropology, EarlyView.
ABSTRACT Global supply chains are saturated with transgressions—corruption, smuggling, document forgery, and other practices that blur the line between legality and illegality. States do not merely endure these practices; they actively shape the conditions for them, producing the very illegal systems they then claim to police.
Dejana Kostić
wiley   +1 more source

Dual use of e-cigarettes and combustible cigarettes elevates salivary DKK1 levels similar to exclusive smoking. [PDF]

Front Public Health
Vázquez-López NI, Falfán-Valencia R, Chavez-Galan L, Fricke-Galindo I, Ramos-Martínez E, Sansores R, Ramirez Venegas A, Rivera-González C, Pérez-Rubio G.   +8 more
europepmc   +1 more source

Microfluidics Lab‐on‐a‐Chip Approaches to Decipher Atherosclerosis Pathogenesis

Small, EarlyView.
Figure created with BioRender.com. This review highlights how microfluidic lab‐on‐a‐chip models recreate key features of atherosclerosis in controlled, human‐relevant environments. It summarizes advances in modeling endothelial dysfunction, immune cell recruitment, foam cell formation, vascular remodeling, stenosis, and plaque rupture.
Fahima Akther, Hang Thu Ta
wiley   +1 more source

Trends in exclusive and dual cigarette and electronic cigarette use among United States middle and high school students from 2017 to 2024: A cross-sectional analysis. [PDF]

Tob Induc Dis
Chen Y, Jimenez-Mendoza E, Jeon J, Meza R.   +3 more
europepmc   +1 more source