Results 231 to 240 of about 440,670 (311)

Recent Progress in Treating Airway Mucus Hypersecretion by Targeting the Epidermal Growth Factor Receptor Signaling Pathway

open access: yesPediatric Discovery, EarlyView.
ABSTRACT Asthma, chronic pulmonary obstructive disease (COPD), cystic fibrosis, and acute respiratory infections are severe respiratory conditions that significantly contribute to global morbidity and mortality. Airway mucus hypersecretion is an important common pathophysiological and clinical manifestation of these diseases and is closely associated ...
Yuanyuan Zhang   +4 more
wiley   +1 more source

Electronic cigarettes and cardiovascular outcomes: a systematic review and meta-analysis of Major Adverse Cardiovascular Events (MACE). [PDF]

open access: yesBMC Public Health
Al-Rubaye SN   +11 more
europepmc   +1 more source

Evaluation of Loss of the Y Chromosome in Peripheral Blood as a Biomarker for Prostate Cancer

open access: yesThe Prostate, EarlyView.
ABSTRACT Background Prostate cancer (PCa) is the most common malignant tumor in men, but the widely used prostate‐specific antigen (PSA) test has limited diagnostic accuracy. Research proposes that the loss of the Y chromosome (LOY) may affect the occurrence and development of prostate cancer, aiming to assess its potential as a diagnostic biomarker to
Jun Lu   +10 more
wiley   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

open access: yesPhytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam   +14 more
wiley   +1 more source

Maximising Participation in the Australian National Lung Cancer Screening Program: A Discrete Choice Experiment of Eligible, High‐Risk Individuals

open access: yesRespirology, EarlyView.
A discrete choice experiment of lung cancer screening attributes. Study results demonstrate that lung cancer screening uptake could be significantly increased by offering program navigators and personalised invitations. The findings contribute significant insights to inform future improvements to the design and implementation of the Australian National
Peiwen Jiang   +10 more
wiley   +1 more source

Development and validation of the Tobacco Use Individual-level Simulation and Tracking (TwIST) Model. [PDF]

open access: yesPLoS One
Mills SD   +6 more
europepmc   +1 more source

[Electronic cigarette: utopia safe cigarette].

open access: yesAtencion primaria, 2015
J A, Ribera Osca   +2 more
openaire   +1 more source

Epigenetic Dysregulation of the NKX2‐1/SPDEF Axis Drives Persistent Goblet Cell Differentiation and Epithelial Barrier Dysfunction in Chronic Obstructive Pulmonary Disease

open access: yesRespirology, EarlyView.
This study investigated airway epithelial barrier dysfunction persistence in ex‐smokers with COPD and underlying mechanisms using single‐cell RNA and ATAC sequencing. Epigenetic NKX2‐1/SPDEF dysregulation maintains goblet cell hyperplasia and barrier dysfunction despite long‐term smoking cessation.
Ayaka Shiota   +17 more
wiley   +1 more source

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