A microscopy-based CRISPR screening platform enables organellar functional genomics and illuminates ciliary biology. [PDF]
Sun J +4 more
europepmc +1 more source
ABSTRACT Background Osseous metaplasia is a rare condition characterized by abnormal bone growth in soft tissues. Although documented in mammals, intraocular osseous metaplasia is uncommon in avian species and has been poorly characterized in turkeys (Meleagris gallopavo).
Taina dos Santos Alberti +6 more
wiley +1 more source
Physics of microbial taxis and behaviours in response to various physical stimuli. [PDF]
Ishikawa T +3 more
europepmc +1 more source
An eye on long‐duration spaceflight: Controversies, countermeasures and challenges
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng +1 more
wiley +1 more source
A CRISPR activation screen reveals a cilia disassembly pathway mutated in focal cortical dysplasia. [PDF]
Elliott SD +13 more
europepmc +1 more source
Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley +1 more source
Brain vascular stability relies on PAK2-cilia-PDGF-BB-HSPGs on basolateral side of endothelium. [PDF]
Prabhudesai S +19 more
europepmc +1 more source
Mitochondrial control of ciliary gene expression and structure in striatal neurons
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen +5 more
wiley +1 more source
Designing enhanced mixing in stagnant microfluidic environments: an artificial cilia approach.
Wang T +6 more
europepmc +1 more source
Sensilla Trichoidea-Inspired, High-Temperature, and Omnidirectional Vibration Perception Based on Monolayer Graphene. [PDF]
Li Y +11 more
europepmc +1 more source

