The ventral root avulsion (VRA) model provides an excellent experimental paradigm for studying injuries at the Central/Peripheral Nervous Systems (CNS/PNS) interface. By physically disconnecting motoneurons (MNs) from the spinal cord surface, VRA induces profound cellular, molecular, and functional deficits with limited spontaneous recovery.
Paola Andrea Caro Aponte +7 more
wiley +1 more source
Primary Cilia and Cardiovascular Risk Factors in Alzheimer's Disease. [PDF]
Sunderman CL +7 more
europepmc +1 more source
Astrocyte Regulation of Spinal Circuit Function
Spinal cord astrocytes exist as an additional component of the computational framework that governs both sensory perceptions and motor outputs (left). By integrating local synaptic activity together with signals that reflect whole‐body state (e.g., neuromodulators, immune signals, and vascular signals) into defined input states (Sn), astrocytes adapt ...
Mary Kaye Duff +2 more
wiley +1 more source
Advanced Microrobots Driven by Acoustic and Magnetic Fields for Biomedical Applications. [PDF]
Wang T, Chen Z, Huang Q, Arai T, Liu X.
europepmc +1 more source
Welfare assessment of turkeys (Meleagris gallopavo gallopavo) on farm
Abstract This Scientific Opinion assesses the welfare of turkeys of all ages (Meleagris gallopavo gallopavo) on farm in relation to the type and condition of the litter, type and availability of enrichment (including covered veranda and outdoor range), space allowance, concentrations of ammonia and carbon dioxide, effective environmental temperature ...
EFSA Panel Animal Health and Animal Welfare (AHAW) +23 more
wiley +1 more source
Electroosmotic flow of Jeffrey ternary hybrid nanofluids in converging-diverging ciliary microvessels. [PDF]
Obalalu AM +4 more
europepmc +1 more source
HOXB4 Promotes Bladder Cancer Progression in Part Through Transcriptional Activation of Smoothened
HOXB4 is overexpressed in bladder cancer and associated with poor prognosis. By transcriptionally activating Smoothened (SMO), HOXB4 amplifies SMO–GLI signaling to promote tumor growth and metastatic behavior. This graphical abstract highlights the HOXB4–SMO axis as a key driver of bladder cancer progression and a potential target for future ...
Zhaoheng Jin +6 more
wiley +1 more source
The Impact of Neurotoxin Proteins Trafficked by Primary Cilia and Extracellular Vesicles in Neurodegenerative Diseases. [PDF]
Danna R +6 more
europepmc +1 more source
Molecular Mechanisms of Chondrocyte Hypertrophy Mediated by Physical Cues and Therapeutic Strategies in Osteoarthritis. [PDF]
Jin GZ.
europepmc +1 more source
Endocardial primary cilia and blood flow regulate EndoMT during endocardial cushion development. [PDF]
Berg K +4 more
europepmc +1 more source

