Results 21 to 30 of about 30,212 (250)
Bioengineering, 2022 There is a lack of physiologically relevant in vitro human kidney models for disease modelling and detecting drug-induced effects given the limited choice of cells and difficulty implementing quasi-physiological culture conditions.
Gabriele Specioso +10 more
doaj +1 more source
Chronic Hypobaric Hypoxia Modulates Primary Cilia Differently in Adult and Fetal Ovine Kidneys
Frontiers in Physiology, 2017 Hypoxic environments at high altitude have significant effects on kidney injury. Following injury, renal primary cilia display length alterations. Primary cilia are mechanosensory organelles that regulate tubular architecture.
Kiumars Shamloo +9 more
doaj +1 more source
Shape-programmable artificial cilia for microfluidics
iScience, 2021 Summary: The artificial ciliary motion has been known not to be hydrodynamically optimal, limiting their associated applications in the microscale flow domain.
Bivas Panigrahi +2 more
doaj
Ependymal cilia beating induces an actin network to protect centrioles against shear stress
Nature Communications, 2018 Ependymal ciliary beating contributes to the flow of cerebrospinal fluid in the brain ventricles and these cilia resist the flow forces. Here the authors show that the assembly of a dense actin network around the centrioles is induced by cilia beating to
Alexia Mahuzier +12 more
doaj +1 more source
Probing cilia-driven flow in living embryos using femtosecond laser ablation and fast imaging [PDF]
, 2009 Embryonic development strictly depends on fluid dynamics. As a consequence, understanding biological fluid dynamic is essential since it is unclear how flow affects development.
Fraser, Scott E. +2 more
core +1 more source
Primary cilia elongation in response to interleukin-1 mediates the inflammatory response [PDF]
, 2012 Primary cilia are singular, cytoskeletal organelles present in the majority of mammalian cell types where they function as coordinating centres for mechanotransduction, Wnt and hedgehog signalling. The length of the primary cilium is proposed to modulate
A. K. T. Wann +51 more
core +2 more sources
Frontiers in Physiology, 2014 Dopamine plays a number of important physiological roles. However, activation of dopamine receptor type-5 (DR5) and its effect in renal epithelial cells have not been studied.
Viralkumar eUpadhyay +5 more
doaj +1 more source
MHD compressible fluid with variable thermal conductivity through a ciliated channel
Advances in Mechanical Engineering, 2021 This paper employs to discuss the cilia induced flow of a compressible Jeffrey fluid with variable characteristic of thermal conductivity. Thermal conductivity is thermally variable. Effects of thermal radiation and MHD are also explored.
Rida Rafaqat, Ambreen Asfar Khan
doaj +1 more source
Disruption of Intraflagellar Transport in Adult Mice Leads to Obesity and Slow-Onset Cystic Kidney Disease [PDF]
, 2007 SummaryThe assembly of primary cilia is dependant on intraflagellar transport (IFT), which mediates the bidirectional movement of proteins between the base and tip of the cilium.
Croyle, Mandy J. +8 more
core +1 more source
Mixing and transport by ciliary carpets: a numerical study [PDF]
, 2013 We use a 3D computational model to study the fluid transport and mixing due to the beating of an infinite array of cilia. In accord with recent experiments, we observe two distinct regions: a fluid transport region above the cilia and a fluid mixing ...
Ding, Yang +3 more
core +3 more sources