Results 31 to 40 of about 11,941 (146)

A new index for characterizing micro-bead motion in a flow induced by ciliary beating: Part I, experimental analysis.

PLoS Computational Biology, 2017
Mucociliary clearance is one of the major lines of defense of the respiratory system. The mucus layer coating the pulmonary airways is moved along and out of the lung by the activity of motile cilia, thus expelling the particles trapped in it.
Mathieu Bottier, Sylvain Blanchon, Gabriel Pelle, Emilie Bequignon, Daniel Isabey, André Coste, Estelle Escudier, James B Grotberg, Jean-François Papon, Marcel Filoche, Bruno Louis   +10 more
doaj   +1 more source

Physiological flow of biomedical compressible fluids inside a ciliated symmetric channel

Advances in Mechanical Engineering, 2020
This article studies the flow induced by cilia for a compressible Jeffrey fluid. The investigation is carried out for electrically conducting magnetohydrodynamic fluid in a space of porous media. The fluid flows inside a two-dimensional symmetric channel.
Anber Saleem, Aleesha Qaiser, Sohail Nadeem   +2 more
doaj   +1 more source

dmrt2 and myf5 Link Early Somitogenesis to Left-Right Axis Determination in Xenopus laevis

Frontiers in Cell and Developmental Biology, 2022
The vertebrate left-right axis is specified during neurulation by events occurring in a transient ciliated epithelium termed left-right organizer (LRO), which is made up of two distinct cell types.
Melanie Tingler, Amelie Brugger, Kerstin Feistel, Axel Schweickert   +3 more
doaj   +1 more source

Development of a Highly Differentiated Human Primary Proximal Tubule MPS Model (aProximate MPS Flow)

Bioengineering, 2023
The kidney proximal tubule (PT) mediates renal drug elimination in vivo and is a major site of drug-induced toxicity. To reliably assess drug efficacy, it is crucial to construct a model in which PT functions are replicated.
Francesca Pisapia, Donovan O’Brien, Elena Tasinato, Kathryn L. Garner, Colin D. A. Brown   +4 more
doaj   +1 more source

Entropy generation optimization of cilia regulated MHD ternary hybrid Jeffery nanofluid with Arrhenius activation energy and induced magnetic field

Scientific Reports, 2023
This study deals with the entropy generation analysis of synthetic cilia using a ternary hybrid nanofluid (Al–Cu–Fe2O3/Blood) flow through an inclined channel.
Nidhish K. Mishra, Bhupendra K. Sharma, Parikshit Sharma, Taseer Muhammad, Laura M. Pérez   +4 more
doaj   +1 more source

The nucleus of endothelial cell as a sensor of blood flow direction

Biology Open, 2013
Summary Hemodynamic shear stresses cause endothelial cells (ECs) to polarize in the plane of the flow. Paradoxically, under strong shear flows, ECs disassemble their primary cilia, common sensors of shear, and thus must use an alternative mechanism of ...
Eugene Tkachenko, Edgar Gutierrez, Semion K. Saikin, Per Fogelstrand, Chungho Kim, Alex Groisman, Mark H. Ginsberg   +6 more
doaj   +1 more source

Mechanisms underlying unidirectional laminar shear stress-mediated Nrf2 activation in endothelial cells: Amplification of low shear stress signaling by primary cilia

Redox Biology, 2021
Endothelial cells are sensitive to mechanical stress and respond differently to oscillatory flow versus unidirectional flow. This review highlights the mechanisms by which a wide range of unidirectional laminar shear stress induces activation of the ...
Tetsuro Ishii, Eiji Warabi, Giovanni E. Mann   +2 more
doaj   +1 more source

Ependyma in Neurodegenerative Diseases, Radiation-Induced Brain Injury and as a Therapeutic Target for Neurotrophic Factors

Biomolecules, 2023
The neuron loss caused by the progressive damage to the nervous system is proposed to be the main pathogenesis of neurodegenerative diseases. Ependyma is a layer of ciliated ependymal cells that participates in the formation of the brain-cerebrospinal ...
Xin-Yu Ma, Ting-Ting Yang, Lian Liu, Xiao-Chun Peng, Feng Qian, Feng-Ru Tang   +5 more
doaj   +1 more source

Fractional generalized Burgers’ fluid flow due to metachronal waves of cilia in an inclined tube

Advances in Mechanical Engineering, 2017
In this study, the cilia-induced flow is discussed for fractional generalized Burgers’ fluid in an inclined tube. The mathematical model of fractional generalized Burgers’ fluid flow is obtained under the long-wavelength approximation.
K Maqbool, AB Mann, AM Siddiqui, S Shaheen   +3 more
doaj   +1 more source

Fractional Burgers Fluid Flow Due to Metachronal Ciliary Motion in an Inclined Tube

Frontiers in Physiology, 2019
Cilia-induced flow of fractional Burgers fluid is studied in an inclined tube for both symplectic and antiplectic wave patterns. The solution of the problem is persued under the long wave length limitation.
Amer Bilal Mann, Sidra Shaheen, Khadija Maqbool, Sébastien Poncet   +3 more
doaj   +1 more source