Results 121 to 130 of about 4,592,681 (317)
Deciphering the skeletal interoceptive circuitry to control bone homeostasis
BMEMat, EarlyView.This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu +7 more
wiley +1 more source
Straight-line and turning locomotion of Paramecia [PDF]
arXiv, 2012 In this fluid dynamics video we investigate the flow field around straight-line swimming and right and left turning Paramecia using micro- particle image velocimetry ({\mu}PIV). A Paramecium controls its ciliary beating to produce different fluid velocities on either side of its body.
arxiv
BMEMat, EarlyView.Efficient drug delivery to the posterior segment of the eye has long been a challenging issue due to the complex ocular barriers. The review focuses on the promise held by nanoplatforms for barrier penetration and the key mechanisms involved, also highlighting their advantages in achieving efficient drug delivery and superior treatment of PSEDs ...
Yifan Shen +7 more
wiley +1 more source
Nature CommunicationsCilia assembly and function rely on the bidirectional transport of components between the cell body and ciliary tip via Intraflagellar Transport (IFT) trains. Anterograde and retrograde IFT trains travel along the B- and A-tubules of microtubule doublets,
Aditya Chhatre +5 more
doaj +1 more source
Predictors of the development of retinal vascular diseases in women after preeclampsia [PDF]
РМЖ "Клиническая офтальмология", 2019 O.V. Kolenko1,2, E.L. Sorokin1,3, N.S. Khodzhaev4, N.V. Pomytkina1, G.V. Chizhova2, A.A. Fil1, Ya.E. Pashentsev1 1Khabarovsk branch of S.N. Fedorov NMRC “MNTK “Eye Microsurgery”, Khabarovsk, Russian Federation 2Postgraduate Institute for ...
O.V. Kolenko +6 more
doaj
Rethinking the cilia hypothesis of hydrocephalus
Neurobiology of Disease, 2022 Dysfunction of motile cilia in ependymal cells has been proposed to be a pathogenic cause of cerebrospinal fluid (CSF) overaccumulation leading to ventricular expansion in hydrocephalus, primarily based on observations of enlarged ventricles in mouse ...
Phan Q. Duy +3 more
doaj
Magnetically-actuated artificial cilia for microfluidic propulsion [PDF]
arXiv, 2009 Natural cilia are hair-like microtubule-based structures that are able to move fluid at low Reynolds number through asymmetric motion. In this paper we follow a biomimetic approach to design artificial cilia lining the inner surface of microfluidic channels with the goal to propel fluid.
arxiv
The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation
Cytoskeleton, EarlyView.ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni +9 more
wiley +1 more source
Dynamics of primary cilia in endothelial and mesenchymal cells throughout mouse lung development
Developmental Dynamics, EarlyView.Abstract Cilia are specialized structures found on a variety of mammalian cells, with variable roles in the transduction of mechanical and biological signals (by primary cilia, PC), as well as in the generation of fluid flow (by motile cilia). Their critical role in the establishment of a left–right axis in early development is well described, as well ...
Stephen Spurgin +8 more
wiley +1 more source