Results 171 to 180 of about 52,619 (331)

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Primary ciliary dyskinesia assessment by means of optical flow analysis of phase-contrast microscopy images

, 2014
Eduardo Parrilla, M Armengot, Manuel Mata, José Manuel Sánchez Vílchez, Julio Cortijo, José L. Hueso, Jaime Riera, David Moratal   +7 more
openalex   +2 more sources

Mathematical model of ciliary flow and entropy for carreau nanofluid with electroosmosis and radiations in porous medium: A numerical work

, 2023
Wafa F. Alfwzan, F.M. Allehiany, Arshad Riaz, Sheraz Sikandar, Ghaliah Alhamzi   +4 more
openalex   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source

The $Ca^{2+}$-activated $Cl^-$ current ensures robust and reliable signal amplification in vertebrate olfactory receptor neurons

, 2018
Activation of most primary sensory neurons results in transduction currents that are carried by cations. One notable exception is the vertebrate olfactory receptor neuron (ORN), where the transduction current is carried largely by the anion $Cl ...
Reingruber, Jürgen, Reisert, Johannes
core  

Evaluation of Acute Exposure to Combustible and Novel Tobacco Products Using an In Vitro Human Airway Organ Tissue Equivalent Model

Journal of Applied Toxicology, EarlyView.
ABSTRACT Despite the well‐known risks of tobacco use, tobacco exposure remains a major contributor to morbidity and mortality worldwide. Although cigarette use has declined, the popularity of novel tobacco products (NTPs), such as electronic cigarettes (ECs) and heated tobacco products (HTPs), has increased.
Timothy S. Leach, Steven Albertson, Phillip W. Clapp, Vikram Surendran, Trang Simon, Eric C. Donny, Stephen J. Walker, Anthony Atala, Sean V. Murphy   +8 more
wiley   +1 more source

DOCK8 deficiency presenting with sclerosing cholangitis, raised immunoglobulin E, and bronchiectasis: A fatal pediatric case report

JPGN Reports, EarlyView.
Abstract Dedicator of cytokinesis 8 (DOCK8) deficiency is a rare autosomal recessive primary immunodeficiency. Patients with DOCK8 deficiency typically present at early age with allergic manifestations, cutaneous and respiratory infections, raised immunoglobulin E, and they have an increased risk of developing malignancies.
Natalia Nedelkopoulou, Kelechi Ugonna, Stephen Hughes, Sanjay Rajwal, Marumbo Mtegha   +4 more
wiley   +1 more source

Rheological Analysis of Thermally Radiative Hyperbolic Tangent Fluid Flow in a Curved Channel Driven by Metachronal Ciliary Waves [PDF]

Zaheer Abbas, Moin‐ud‐Din Junjua, Melis Arslan, Sabeeh Khaliq, Muhammad Yousuf Rafiq   +4 more
openalex   +1 more source

The Impact of Estrogen on Stromal Elements in the Proximal Airway in Idiopathic Subglottic Stenosis

The Laryngoscope, EarlyView.
ABSTRACT Objectives Idiopathic subglottic stenosis (iSGS) is an unexplained fibrosis of the proximal airway that predominantly impacts Caucasian women. Clinically, premenopausal patients suffer from higher recurrence rates, potentially implicating ovarian hormone 17B‐estradiol (E2) in disease pathogenesis.
Emily L. Mace, Evan Clark, Edward Talatala, Maxim Litvak, Matthew A. Buendia, Yash A. Choksi, Hongmei Wu, Yueli Zhang, Alexander Hillel, Sam Collins, Quanhu Sheng, Jing Yang, Jason Park, Alexander Gelbard   +13 more
wiley   +1 more source

Spatially Organized Ciliary Beating Compartmentalizes Cerebrospinal Fluid Flow in the Brain and Regulates Ventricular Development

, 2018
Emilie Willoch Olstad, Christa Ringers, Adinda Wens, Jan N. Hansen, Cecilia Brandt, Emre Yaksi, Nathalie Jurisch‐Yaksi   +6 more
openalex   +1 more source