Results 251 to 260 of about 4,592,681 (317)

Deficiency of Aging‐Related Gene Chitinase‐Like 4 Impairs Olfactory Epithelium Homeostasis

Cell Proliferation, EarlyView.
Deficiency of Chil4 impairs OE homeostasis through loss of sustentacular cells and a specific type of immature sensory neuron, cell cycle arrest in globose basal cells, and inflammatory activation in microglia‐like cells. ABSTRACT Mammalian olfactory epithelium (OE) undergoes consistent self‐renewal throughout life.
Tingting Wu, Weihao Li, Liujing Zhuang, Jinxia Liu, Ping Wang, Ye Gu, Yongliang Liu, Yiqun Yu   +7 more
wiley   +1 more source

Donor-derived airway ALI model for high-throughput screening of antiviral combinations with concurrent analysis of antiviral efficacy and epithelial toxicity using ciliR

Cardinale D, Grant O, Hyang Lee DD, Hynds RE, Angell R, O’Callaghan C, Cortina-Borja M, Thomas E, Smith CM.   +8 more
europepmc   +1 more source

Ciliary and Non-Ciliary Roles of IFT88 in Development and Diseases. [PDF]

Int J Mol Sci
Wang X, Yin G, Yang Y, Tian X.
europepmc   +1 more source

WHO Reporting System for Lung Cytopathology: Insights Into the Insufficient/Inadequate/Non‐Diagnostic, Atypical and Suspicious for Malignancy Categories and How to Use Them

Cytopathology, EarlyView.
The WHO System is an international effort to standardise category definitions, establish the key diagnostic cytopathological features of entities of the lung, propose the best use of ancillary tests in lung specimens, encourage the use of standardised pathology reports containing essential components in an integrated report and propose estimates of the
Zahra Maleki, Sule Canberk, Andrew Field
wiley   +1 more source

Primary cilia and cancer: a tale of many faces. [PDF]

Oncogene
Collinson R, Tanos B.
europepmc   +1 more source

Clinical features and outcomes of horses presenting with presumed equine immune mediated keratitis to two veterinary hospitals in the United Kingdom and Finland: 94 cases (2009–2021)

Equine Veterinary Journal, Volume 57, Issue 3, Page 598-610, May 2025.
Abstract Background There is limited literature regarding equine immune mediated keratitis (IMMK) in Europe. North America‐based publications describe minimal blepharospasm, rare corneal ulceration and no uveitis; clinical impression suggests these are seen in Europe. Objectives Assess the prevalence of blepharospasm, corneal ulceration and uveitis and
Juliette F. Preston, Minna P. Mustikka, Simon L. Priestnall, Bettina Dunkel, Maria‐Christine Fischer   +4 more
wiley   +1 more source

Mutations in NEK1 cause ciliary dysfunction as a novel pathogenic mechanism in amyotrophic lateral sclerosis. [PDF]

Mol Neurodegener
Noh MY, Oh SI, Kim YE, Cha SJ, Sung W, Oh KW, Park Y, Mun JY, Ki CS, Nahm M, Kim SH.   +10 more
europepmc   +1 more source

Therapeutic targeting of TGF‐β in lung cancer

The FEBS Journal, Volume 292, Issue 7, Page 1520-1557, April 2025.
Here, we discuss how lung cancer treatment can be transformed by targeting TGF‐β for better outcomes. Inhibiting TGF‐β signaling halts tumor growth, boosts immune response, and enhances treatment efficacy. By tackling TGF‐β's role in epithelial–mesenchymal transition (EMT) and immune evasion, this approach opens new avenues for more effective lung ...
Sajjad Aftabi, Amir Barzegar Behrooz, Marco Cordani, Niloufar Rahiman, Mohammadamin Sadeghdoust, Farnaz Aligolighasemabadi, Stephen Pistorius, Seyedeh Hoda Alavizadeh, Nima Taefehshokr, Saeid Ghavami   +9 more
wiley   +1 more source

A tale of Rabs and the exocyst complex in ciliary trafficking and biogenesis. [PDF]

Front Cell Dev Biol
Upadhyai P, Bose D, Quadri N.
europepmc   +1 more source

Evaluating the outcomes of pluripotent stem‐cell‐derived photoreceptor transplantation in retinal repair

The FEBS Journal, EarlyView.
Transplantation of stem cell‐derived photoreceptors in retinal repair. We summarize methods for differentiating stem cells and describe surgical techniques for transplanting photoreceptor precursors to restore visual function (A). The effectiveness of these techniques is assessed with behavioral (B) and in vitro assays (C) using mouse models that mimic
Darin Zerti, Birthe Dorgau, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako, Gerrit Hilgen   +5 more
wiley   +1 more source