Results 171 to 180 of about 9,869 (268)

Identification of Novel Interacting Proteins of FUZ and GPR161

PROTEOMICS, EarlyView.
ABSTRACT Protein–protein interactions are central to the dynamic regulation of signaling pathways and provide critical insight into the cellular mechanisms underlying human disease. Our previous study demonstrated biochemical and genetic interactions between FUZ and GPR161 in sonic hedgehog signaling during spinal neural tube development. In this study,
Gabriella Salazar, Anna Battenhouse, Andrew J. Kim, Sung‐Eun Kim   +3 more
wiley   +1 more source

Biocontrol potential and molecular basis of predation in a marine raptorial ciliate. [PDF]

ISME J
Pan J, Ni J, Wang Y, Deng Z, Yue H, Dong K, Li Y, Lei Z, Ma Z, Hu G, Chi R, Chang Z, Chen Q, Cai Y, Shen H, Shi R, Yang W, Fan X, Li W, Ye Z, Lynch M, Zhang Y, Long H.   +22 more
europepmc   +1 more source

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

Portal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao, Sheng Cheng, Qiaoling Pan, Jiong Yu, Hongcui Cao   +4 more
wiley   +1 more source

Cross-domain transfer of trehalose biosynthesis genes contributes to adaptation in high-altitude environments. [PDF]

Natl Sci Rev
Wang Y, Ni J, Pan J, Feng R, Li W, Zhang X, Gao C, Liao L, Zhang Z, Yue H, Zhang K, Zhang L, Feng C, Yao D, Han Y, Li X, Zhou X, Deng Z, Zhang J, Zhou P, Jing G, Zhang Y, Chen L, Pan X, Chen X, Bai Y, Yan Y, Huang J, Ye Z, Shen X, Tian M, Zufall RA, Wang P, Lynch M, Long H.   +34 more
europepmc   +1 more source

Neurotrophic Signaling, Sleep Physiology, and Retinal Neuroprotection: Integrative Mechanisms and Therapeutic Implications for Glaucoma

Sensory Neuroscience, EarlyView.
Glaucoma is increasingly understood as a neurodegenerative disorder shaped by sleep and circadian physiology, not intraocular pressure alone. Sleep loss and obstructive sleep apnea suppress BDNF–TrkB neurotrophic signaling, impair sleep‐dependent glymphatic clearance, and trigger microglial neuroinflammation and vascular insult at the optic nerve head,
Karyme M. Alemán‐Villa, Emiliano Terán, Javier A. Magaña‐Gómez, Loranda Calderón‐Zamora, Beatriz K. De la Herrán‐Arita, Alberto K. De la Herrán‐Arita   +5 more
wiley   +1 more source

Direction and Progression of Thermal Acclimation Effects on Ciliated Protist Populations Both Depend on Direction of Thermal Change. [PDF]

Ecol Evol
Bebout J, Fox JW.
europepmc   +1 more source

Polymersome‐Enabled Multimodal Delivery of Tobramycin and Doripenem for Targeted Eradication of Pseudomonas aeruginosa Biofilms in Chronic Rhinosinusitis

Small, EarlyView.
Schematic representation of diffusion‐based versus pH‐triggered drug release within a bacterial biofilm. In diffusion‐based systems, drug cargo is gradually released independent of local pH, resulting in rapid burst release and reduced sustained concentrations.
Amalie Kjær Andresen, Matteo Tollemeto, Alexander B. Cook, Claus Sternberg, Yudong Li, Claus Moser, Lars Jelsbak, Jan C. M. Van Hest, Anja Boisen, Line Hagner Nielsen   +9 more
wiley   +1 more source

On the ecological duality between ciliates and dinoflagellates across marine ecosystems. [PDF]

J Plankton Res
Calbet A.
europepmc   +1 more source

Effects of Glyphosate on the Planktonic Microbiota: An Experimental Approach

Environmental Toxicology, EarlyView.
ABSTRACT Glyphosate is one of the most widely used herbicides in the world, including in Brazil, and its dispersion through habitats and surface waters can impact entire aquatic ecosystems. However, experimental studies evaluating the effects of pesticides on whole planktonic communities, considering attributes such as richness, density and composition—
Melissa Progênio, Matheus Henrique Oliveira de Matos, Edilaine Corrêa Leite, Bianca Ramos de Meira, João Vitor Bredariol, José Eduardo Gonçalves, Pablo Augusto Poleto Antiqueira, Luiz Felipe Machado Velho   +7 more
wiley   +1 more source

<i>Arachniodes × tohtomiensis</i> hyb. nov. (Dryopteridaceae) from Japan. [PDF]

PhytoKeys
Hori K, Takahashi D, He YH, Shin T, Suyama Y.   +4 more
europepmc   +1 more source