Results 11 to 20 of about 374 (127)

Cimicifugoside H-2 as an Inhibitor of IKK1/Alpha: A Molecular Docking and Dynamic Simulation Study [PDF]

Biomolecules
One of the most challenging issues scientists face is finding a suitable non-invasive treatment for cancer, as it is widespread around the world. The efficacy of phytochemicals that target oncogenic pathways appears to be quite promising and has gained ...
Shahd Aboul Hosn, Christina El Ahmadieh, Sergio Thoumi, Aia Sinno, Charbel Al Khoury   +4 more
doaj   +2 more sources

Effect of the standardized Cimicifuga foetida extract on Hsp 27 expression in the MCF-7 cell line [PDF]

Biological Research, 2011
Cimicifuga foetida, an Asian Cimicifuga species, has been employed as a cooling and detoxification agent in traditional Chinese medicine since ancient times.
Maritza C Soler, Jessica L Molina, Hugo A Díaz, Vivian C Pinto, Yasenka L Barrios, Kan He, Marc Roller, Caroline R Weinstein-Oppenheimer   +7 more
doaj   +4 more sources

Methanolic Extract of Cimicifuga foetida Induces G₁ Cell Cycle Arrest and Apoptosis and Inhibits Metastasis of Glioma Cells. [PDF]

Nutrients
Background: Glioblastoma multiforme (GBM) is among the most aggressive and challenging brain tumors, with limited treatment options. Cimicifuga foetida, a traditional Chinese medicine, has shown promise due to its bioactive components. This study investigates the anti-glioma effects of a methanolic extract of C.
Chang CH, Tsai HP, Yen MH, Lin CJ.
europepmc   +3 more sources

Five New Triterpene Bisglycosides with Acyclic Side Chains from the Rhizomes of Cimicifuga foetida L.

Chemical and Pharmaceutical Bulletin, 2010
Five new triterpene bisglycosides, foetidinosides A (1), B (2), C (3), D (4) and E (5), including three of the cycloartane type, one of its derivative, and one of the lanostane type were isolated from the rhizomes of Cimicifuga foetida. Their structures were elucidated on the basis of spectroscopic data and chemical evidence.
Lu Lu, Jian-Chao Chen, Yin Nian
exaly   +4 more sources

A Case of Severe Anemia in Pregnancy Treated With Traditional Chinese Medicine. [PDF]

Clin Case Rep
ABSTRACT This case report describes the treatment of a 29‐year‐old pregnant woman with severe anemia using traditional Chinese medicine (TCM). The patient, at 5 weeks of gestation, presented with a hemoglobin level of 75 g/L and had a history of autoimmune hemolytic anemia and alpha‐thalassemia, which had previously led to pregnancy termination at 17 ...
Zhong S, Xie T.
europepmc   +2 more sources

Ferulic Acid Alleviates Inflammation and Promotes Osteogenic Differentiation in Periodontitis by Inhibiting NF-<i>κ</i>B Pathway. [PDF]

Stem Cells Int
Background Periodontitis refers to a chronic inflammatory illness that induces the destruction of periodontal tissues and can be driven by bacterial lipopolysaccharide (LPS) of pathogens. This study investigated the anti‐inflammatory potential and underlying mechanisms of ferulic acid (FA) in periodontitis.
Wang Q, Feng B, Gao Y.
europepmc   +2 more sources

Secondary Metabolites with Anti-Inflammatory from the Roots of Cimicifuga taiwanensis

Molecules, 2022
The genus Cimicifuga is one of the smallest genera in the family Ranunculaceae. Cimicifugae Rhizoma originated from rhizomes of Cimicifuga simplex, and C. dahurica, C. racemosa, C. foetida, and C.
Jih-Jung Chen, Ming-Jen Cheng, Tzong-Huei Lee, Yueh-Hsiung Kuo, Chao-Tsen Lu   +4 more
doaj   +1 more source

Ferulic acid as a therapeutic agent in depression: Evidence from preclinical studies

CNS Neuroscience &Therapeutics, Volume 29, Issue 9, Page 2397-2412, September 2023., 2023
Abstract Depression is a common but severe mood disorder with a very high prevalence across the general population. Depression is of global concern and poses a threat to human physical and mental health. Ferulic acid (FA) is a natural active ingredient that has antioxidative, anti‐inflammatory, and free radical scavenging properties.
Xiaoyu Dong, Dongxue Zhao
wiley   +1 more source

TCM Prescription Generation via Knowledge Source Guidance Network Combined with Herbal Candidate Mechanism

Computational and Mathematical Methods in Medicine, Volume 2023, Issue 1, 2023., 2023
Traditional Chinese medicine (TCM) prescriptions have made great contributions to the treatment of diseases and health preservation. To alleviate the shortage of TCM resources and improve the professionalism of automatically generated prescriptions, this paper deeply explores the connection between symptoms and herbs through deep learning technology ...
Jiaxin Hou, Ping Song, Zijuan Zhao, Yan Qiang, Juanjuan Zhao, Qianqian Yang, Sathishkumar V E   +6 more
wiley   +1 more source

Plants in Anticancer Drug Discovery: From Molecular Mechanism to Chemoprevention

BioMed Research International, Volume 2022, Issue 1, 2022., 2022
Cancer is one of the primary causes of mortality globally, and the discovery of new anticancer drugs is the most important need in recent times. Natural products have been recognized as effective in fight against various diseases including cancer for over 50 years.
Arif Jamal Siddiqui, Sadaf Jahan, Ritu Singh, Juhi Saxena, Syed Amir Ashraf, Andleeb Khan, Ranjay Kumar Choudhary, Santhanaraj Balakrishnan, Riadh Badraoui, Fevzi Bardakci, Mohd Adnan, Yearul Kabir   +11 more
wiley   +1 more source