Results 111 to 120 of about 88,977 (256)

LGM glaciation in the northern Dinaric Mountains, Slovenia: new insights from terrestrial cosmogenic nuclide dating and Parallel Ice Sheet Model simulation

Boreas, EarlyView.
The Dinaric Mountains are a mountain range stretching NW–SE from the Alps to the Albanides–Hellenides in central Europe. The highest parts were occupied by small ice fields and/or valley glaciers during the Quaternary cold periods, while even today some small glaciers still exist in topoclimatically favourable areas.
Manja Žebre, M. Akif Sarikaya, Matjaž Depolli, Uroš Stepišnik, Attila Çiner, Gregor Kosec, Klaus Wilcken, Cengiz Yildirim   +7 more
wiley   +1 more source

MCL‐1 inhibition triggers a largely reversible cardiac stress signature in a humanised mouse model

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Myeloid cell leukaemia‐1 (MCL‐1) is an essential anti‐apoptotic protein and a promising therapeutic target in oncology. Early clinical studies of MCL‐1 inhibitors reported unexpected elevations in cardiac troponin, raising concerns about potential cardiotoxicity.
Markus B. Heckmann, Zsanett Papdi, Nils J. Strauch, Daniel Finke, Marc‐Steffen Raab, Antje Blank, Norbert Frey, Lorenz H. Lehmann   +7 more
wiley   +1 more source

Continuing Professional Development—Radiation Therapy

Journal of Medical Radiation Sciences, Volume 72, Issue 1, Page 174-174, March 2025.
wiley   +1 more source

Navigating the Zero Fluoroscopy Frontier: Current Tools, Evidence and Future Directions in Electrophysiology Procedures

Pacing and Clinical Electrophysiology, EarlyView.
Graphical Abstract ABSTRACT Fluoroscopy has traditionally been the mainstay imaging technique for guidance during electrophysiology (EP) ablation procedures. The numerous disadvantages associated with radiation exposure for both operators and patients have created the need for zero‐fluoroscopy (ZF) approaches. Today, electrophysiologists have access to
Dimitrios Kotzadamis, Georgios Giannopoulos, Vaios Schismenos, Alexandros Evangeliou, Prokopios Mamolis, Antonios Antoniadis, Vassilios Vassilikos   +6 more
wiley   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Impaired Windkessel function and proximal aortic stiffness: Linking vascular ageing to cognitive decline

Experimental Physiology, EarlyView.
Abstract Central arterial stiffening, particularly of the proximal aorta, is increasingly recognised as a pivotal contributor to cardiovascular disease, dementia, and mild cognitive impairment. Loss of Windkessel function amplifies pulsatile pressure, reduces diastolic perfusion and accelerates microvascular damage in the brain.
Jun Sugawara, Hirofumi Tanaka
wiley   +1 more source

Lower limb blood flow responses during higher‐ and lower‐load bilateral leg press exercise

Experimental Physiology, EarlyView.
Abstract The local blood flow response to resistance exercise (RE) is complicated by local muscular contractions and large swings in perfusion pressure. The magnitude of these responses might vary according to exercise intensity, number of sets and number of repetitions, and as a result, the local shear environment during RE remains uncharacterized. We
Eudoxia Zafiris, Jeremy. N. Cohen, Tania J. Pereira, Jason S. Au   +3 more
wiley   +1 more source

Sex differences in cerebral blood flow and cardiac function in response to exercise in the heat

Experimental Physiology, EarlyView.
Abstract We investigated the effect of exercising in hot conditions on cerebral blood flow and systolic left ventricular (LV) function in males and females, to explore sex differences. The experimental condition consisted of walking on a treadmill at 5 km/h and 2% incline, inside a heat chamber at 40°C (50% relative humidity), for 90 min.
João Carlos Locatelli, Juliene G. Costa, Kristanti W. Wigati, Jesse L. Criddle, Julie J. Collis, Xingwei Xu, Louise H. Naylor, Howard H. Carter, Shane K. Maloney, Robert A. McLaughlin, Andrew Haynes, Helen Jones, Keith George, Daniel J. Green   +13 more
wiley   +1 more source

Variance Extrapolated Class-Imbalance-Aware Domain Adaptive Myocardial Segmentation in Multi-Sequence Cardiac MRI. [PDF]

IEEE J Biomed Health Inform
Xing F, Liu X, Aganj I, Fakhri GE, Kim P, Choi BW, Woo J.   +6 more
europepmc   +1 more source

Pressure‐dependent coupling between arterial pressure and intercostal muscle blood‐flow index during acute hypotension in humans

Experimental Physiology, EarlyView.
Abstract Regulation of respiratory muscle blood flow during acute systemic hypotension remains poorly understood in humans because continuous assessment of microvascular perfusion during rapid haemodynamic transients has been technically challenging. Using diffuse correlation spectroscopy, we investigated second‐by‐second coupling between mean arterial
Masashi Ichinose, Mikie Nakabayashi, Yumie Ono   +2 more
wiley   +1 more source