Results 201 to 210 of about 18,245 (244)
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Toxicokinetics of cinnamaldehyde in F344 rats
Food and Chemical Toxicology, 1992The toxicokinetic profile of cinnamaldehyde (CNMA) was investigated in Fischer 344 rats. CNMA was found to be unstable in blood. After iv administration, a large fraction of CNMA was immediately oxidized to cinnamic acid. The biological half-life of CNMA after iv administration was found to be 1.7 hr.
J H, Yuan +3 more
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Australian Journal of Chemistry, 1979
4-Hydroxy-3,5-dimethoxycinnamaldehyde, 3,4,5-trimethoxycinnamaldehyde and 3,4-dimethoxy-cinnamaldehyde were synthesized for biological testing. The Wittig synthesis of a, ß-unsaturated aldehydes, using formylmethylenetriphenylphosphorane, was developed as a general method for the preparation of the required substituted cinnamaldehydes.
R Olstein, EFM Stephenson
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4-Hydroxy-3,5-dimethoxycinnamaldehyde, 3,4,5-trimethoxycinnamaldehyde and 3,4-dimethoxy-cinnamaldehyde were synthesized for biological testing. The Wittig synthesis of a, ß-unsaturated aldehydes, using formylmethylenetriphenylphosphorane, was developed as a general method for the preparation of the required substituted cinnamaldehydes.
R Olstein, EFM Stephenson
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Cinnamaldehyde Analogues as Potential Therapeutic Agents
Mini-Reviews in Medicinal Chemistry, 2016Cinnamaldehyde analogues are a class of chemical substances originated from derivatization of cinnamaldehyde, and are structurally characterized by the presence of cinnamoyl moiety. Due to the presence of highly reactive α,α-unsaturated carbonyl pharmacophore (Michael acceptor) in their structures, these molecules are apt to react ...
Xiao-Ning Wang, Dongmei Ren, Tao Shen
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Reaction of dodecacarbonyltriruthenium with cinnamaldehyde
Russian Chemical Bulletin, 1998The reaction of dodecacarbonyltriruthenium with cinnamaldehyde yielded a mixture of the known H4Ru4(CO)12, H2Ru4(CO)13, and H2Ru6(CO)18, and Ru6C(CO)17 clusters and the 1,1,1,2,2,2,3,3,3-nonacarbonyl-1,2;1,3-(μ3-dihydrido)-1,3-σ;2-π-[μ3-η2-(pheny)vinylidene]triangulotriruthenium complex. The structure of the last-mentioned compound was established by X-
M. I. Rybinskaya +5 more
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Contact urticarial skin responses to cinnamaldehyde
Contact Dermatitis, 1977A patient suffering from an eczema of the right hand showed after routine patch testing an immediate urticarial reaction to cinnamaldehyde.The same reaction could be noted in three out of eight control persons. Laboratory investigations revealed cinnamaldehyde to have a histamine liberating effect, a fact not previously mentioned in reports on untoward
NATER, JP +3 more
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Electrohydrodimerization of trans-cinnamaldehyde
Tetrahedron, 1997Abstract The electrochemical reduction of trans-cinnamaldehyde in protic medium (MeOH-NaClO4) on a mercury cathode gives four cyclic hydrodimeric products in 80% yield, through a “head to tail” coupling pathway. The different anomers were identified as (±)-c-4-phenyl-t-5-[(E)-styryl]tetrahydrofuran-r-2-ol, (±)-t-4-phenyl-c-5-[(E)-styryl ...
Fructuoso Barba +2 more
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The retroaldol reaction of cinnamaldehyde
Canadian Journal of Chemistry, 1984Rate and equilibrium constants have been measured for the hydration and retroaldol reactions of cinnamaldehyde. The equilibrium constant for the 1,4-addition of water to cinnamaldehyde is 4.42 × 10−3. The rate constants for hydroxide catalyzed reaction, extrapolated to zero hydroxide concentration (to correct for the addition of hydroxide to the aldol
J. Peter Guthrie +4 more
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Effects of Cinnamaldehyde on Smooth Muscle Preparations
Pharmacology, 2019The effects of cinnamaldehyde (CNA), known as a transient receptor potential ankyrin 1 (TRPA1) agonist, on guinea-pig ileum and urinary bladder were studied in isolated organ experiments. Contractile effects were found to be present on both preparations.
Zsolt Istvan, Sandor +3 more
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Influence of Cinnamaldehyde on Viral Myocarditis in Mice
The American Journal of the Medical Sciences, 2010This study was designed to examine the effects of cinnamaldehyde on coxsackievirus B3 (CVB3)-induced viral myocarditis (VMC) and underlying signaling, with a focus on the toll-like receptor (TLR)4-nuclear factor (NF)-kappaB pathway.The antiviral and myocardial effects of cinnamaldehyde and its metabolite cinnamic acid were evaluated both in vitro and ...
YuanYuan, Ding +4 more
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Reduction of cinnamic acid to cinnamaldehyde and alcohol
Biochemical and Biophysical Research Communications, 1968Abstract The reduction of the carboxylgroup of phenylacrylic acids to form aldehydes and primary alcohols has long been inferred in the formation of lignin. In spite of the fact, that the stepwise reduction of ferulic acid (3-methoxy-4-hydroxycinnamic acid) to coniferylaldehyde and alcohol during the formation of lignin has been demonstrated in ...
G G, Gross, K H, Bolkart, M H, Zenk
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