Results 91 to 100 of about 3,591 (202)

Aprepitant, a novel neurokinin-1 receptor antagonist in management of chemotherapy induces nausea vomiting (CINV) in cancer patients

, 2019
Nausea and emesis are two major concerns for patients undergoing chemotherapy for cancer. The 5HT3 receptors antagonist ondansetron is the major factor for preventing and treatment for CINV either alone or often is combination with dexamethasone.
Shaik Habeebjan, Robin George, E. Sunil Kumar, Kondi Charitha Reddy   +3 more
core  

He-Wei granules inhibit chemotherapy-induced vomiting (CINV) in rats by reducing oxidative stress and regulating 5-HT, substance P, ghrelin and obestatin

, 2017
As a common side effect of a variety of chemotherapy drugs, CINV severely limits the clinical use of chemotherapy drugs.
Hang Chang, Jun Yin, Zhonglin Wang, Na Han, Zhihui Liu, Hao Gao, Zehai Song   +6 more
core   +1 more source

Abstract P2-11-01: Non interventional study with netupitant/ palonosetron (NEPA) as CINV prophylaxis in highly or moderately emetogenic chemotherapy

, 2017
Background Nausea and Vomiting due to cancer therapy is still a problem for patients and physicians and therefore an ongoing item of research in oncology. International antiemetic guidelines (ASCO, NCCN, MASCC/ESMO) have been published and
D Guth, P Klare, M Karthaus, JP Schilling, PA Ortner   +4 more
core   +1 more source

A systemic review on chemotherapy induced nausea and vomiting- risk and clinical management with alternative therapies

Cancer Treatment and Research Communications
Chemotherapy-induced nausea and vomiting (CINV) affects up to 80 % of cancer patients, significantly impacts the health in terms of their quality of life and straining healthcare resources. CINV is categorized into anticipatory, acute, and delayed types.
Derangula Lavanya, VelugotlaPranathi Prasanna, Asma Firdous, Sneha Thakur   +3 more
doaj   +1 more source

Rolapitant for control of chemotherapy-induced nausea and vomiting (CINV) in patients with gynecologic cancer.

, 2016
223 Background: Rolapitant, a long-acting neurokinin-1 receptor antagonist, protected against CINV in patients receiving highly or moderately emetogenic chemotherapy (HEC or MEC).
Daniel Powers, Bernardo Leon Rapoport, Lee Steven Schwartzberg, Karin Jordan, Sujata Arora, Rudolph M. Navari   +5 more
core   +1 more source

Palonosetron, second generation 5-HT3 antagonist: a new perspective in CINV management

, 2006
It is well established that the majority of cancer patients who undergo moderately or highly emetogenic cytotoxic treatment without receiving prophylactic antiemetics will experience chemotherapy-induced nausea and vomiting (CINV).
PICCALUGA, PIER PAOLO
core   +1 more source

Profile of netupitant/palonosetron (NEPA) fixed dose combination and its potential in the treatment of chemotherapy-induced nausea and vomiting (CINV)

, 2014
Rudolph M Navari Cancer Care Program, Eastern Europe, World Health Organization, Mishawaka, IN, USA; Indiana University School of Medicine, South Bend, IN, USA; South Bend Medical Services Corporation, IN, USA Abstract: Chemotherapy-induced ...
Navari RM, Navari, Rudolph M.
core   +1 more source

Meta-analysis of trials comparing standard antiemetic treatment (SAT) with aprepitant containing antiemetic regimens (ACAR) for prevention of chemotherapy-induced nausea and vomiting (CINV).

, 2014
171 Background: Various randomized controlled trials (RCTs) have shown improved outcomes with addition of aprepitant to standard antiemetic treatment (SAT) in preventing CINV.
Roberto Pili, Hassan Hatoum, Omar Al Ustwani, Neha Gupta, Pongwut Danchaivijitr, Katy Wang   +5 more
core   +1 more source

Efficacy of The Ginger on Chemotherapy-Induced Nausea and Vomiting (CINV): A Systematic Review [PDF]

, 2018
Background: Chemotherapy Induced Nausea-Vomiting (CINV) is a frequent side effect experienced by sufferers of malignant tumor undergoing chemotherapy. Ginger is one herb that has been used since many years and is naturally especially as antiemetic.
Fatimah, Zahra, I Komang, Leo Triandana Arizona, Titis, Eka Apriliyanti   +2 more
core  

A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high dose cisplatin

, 2017
The activity of ginger in the management of chemotherapy-induced nausea and vomiting (CINV) has been suggested, but design inadequacies, heterogeneity of the population, small numbers and poor quality of tested products limit the possibility to offer ...
Montanaro, F, Bossi, P, D. Cortinovis, P. Bidoli, Fatigoni, S, Ripamonti, C, Pessi, M A, Cossu Rocca, M, Nolè, F, A. Fabi, Roila, F., F. Nolè, Michellini, L, F. Macchi, SEMINARA, Patrizia, P. Bossi, L. Michellini, M. Cossu Rocca, Macchi, F, C. Bergamini, C. Ripamonti, F. Agustoni, M.A. Pessi, Cortinovis, D, Fabi, A, Granata, R, Bergamini, C, S. Fatigoni, Seminara, P, Alfieri, S, Pessi, M. A, F. Montanaro, F. Roila, Roila, F, Bidoli, P, R. Granata, P. Seminara, S. Alfieri, Agustoni, F   +38 more
core   +1 more source