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Integrating nutrition, physical exercise, psychosocial support and antiemetic drugs into CINV management: The road to success [PDF]
Critical Reviews in Oncology/HematologyOver the years, advancements in antiemetic drugs have improved chemotherapy-induced nausea and vomiting (CINV) control. However, despite the antiemetics therapies, in a relevant number of adult patients (similar to 30 %), CINV is still persistent ...
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Cancer Research, 2021
Abstract Background: CINV remains a challenging chemotherapy toxicity, particularly for anthracyclines + cyclophosphamide (AC) for breast cancer. Complete response (CR), defined as no vomiting or use of rescue medication over 5 days after chemotherapy, has been the standard endpoint for successful antiemetic prophylaxis, yet duration of ...
Rudolph M. Navari +11 more
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Abstract Background: CINV remains a challenging chemotherapy toxicity, particularly for anthracyclines + cyclophosphamide (AC) for breast cancer. Complete response (CR), defined as no vomiting or use of rescue medication over 5 days after chemotherapy, has been the standard endpoint for successful antiemetic prophylaxis, yet duration of ...
Rudolph M. Navari +11 more
openaire +1 more source
2016
Antiemetic guidelines have been published by NCCN [1], ASCO [2], and MASCC [3]. These guidelines form the basis for the recommendations for the management of CINV. As new information and new studies emerge, the guidelines will evolve to provide the highest quality evidence-based clinical practice.
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Antiemetic guidelines have been published by NCCN [1], ASCO [2], and MASCC [3]. These guidelines form the basis for the recommendations for the management of CINV. As new information and new studies emerge, the guidelines will evolve to provide the highest quality evidence-based clinical practice.
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Gabapentin for the Prevention of CINV
2016Gabapentin is a gamma-aminobutyric acid (GABA) analogue initially approved by the Food and Drug Administration (FDA) in 1993 for the treatment of seizures. Gabapentin was soon found to be highly effective for treating neuropathic pain [1] and then restless legs syndrome [2] and presently is FDA approved for all three indications.
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Gynecologic Oncology, 2016
This study was performed to investigate the occurrence of and risk factors for chemotherapy-induced nausea and vomiting (CINV) in patients with gynecologic cancer.In total, 214 patients with gynecologic cancer who underwent highly emetogenic (HEC) or moderately emetogenic chemotherapy (MEC) were evaluated.
Mika Mizuno +11 more
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This study was performed to investigate the occurrence of and risk factors for chemotherapy-induced nausea and vomiting (CINV) in patients with gynecologic cancer.In total, 214 patients with gynecologic cancer who underwent highly emetogenic (HEC) or moderately emetogenic chemotherapy (MEC) were evaluated.
Mika Mizuno +11 more
openaire +2 more sources
CINV in the UK: a prospective audit of patient experience
British Journal of Nursing, 2011Chemotherapy induces nausea and vomiting in a significant number of cancer patients across the world each day. Unfortunately patients tend to be at home and away from the specialist oncology centres when the symptoms are at their worst. This leads to a disconnect between what health professionals predict will happen to patients and what patients ...
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Supportive Care in Cancer, 2014
We sought to describe the impact of chemotherapy-induced nausea and vomiting (CINV) in prior cycles on CINV and chemotherapy regimen modification in subsequent cycles.Eligible patients in this multinational prospective observational study were adults (≥18 years old) receiving their first single-day highly or moderately emetogenic chemotherapy (HEC or ...
Hoon-Kyo, Kim +9 more
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We sought to describe the impact of chemotherapy-induced nausea and vomiting (CINV) in prior cycles on CINV and chemotherapy regimen modification in subsequent cycles.Eligible patients in this multinational prospective observational study were adults (≥18 years old) receiving their first single-day highly or moderately emetogenic chemotherapy (HEC or ...
Hoon-Kyo, Kim +9 more
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Overview of the prevention and management of CINV.
The American journal of managed care, 2020The prevention of chemotherapy-induced nausea and vomiting (CINV) is critically important in reducing morbidity and total healthcare costs in patients receiving emetogenic chemotherapy. The different types of CINV (ie, acute, delayed, anticipatory, breakthrough, and refractory) are controlled through various pathways and neurotransmitters, so the ...
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Pharmacoeconomic considerations of tropisetron for prophylaxis and treatment of CINV and PONV
Expert Review of Pharmacoeconomics & Outcomes Research, 2003Postoperative nausea and vomiting has been described as the big little problem in anesthesia, with the overall incidence after anesthesia using volatile anesthetics remaining between 20 and 30%. In patients who receive ambulatory surgery, postoperative nausea and vomiting may lead to delayed discharge or unplanned overnight admission to hospital which ...
Caroline D, Kratz +3 more
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Lange Halbwertszeit erleichtert CINV-Prophylaxe
Im Focus Onkologie, 2017Nach wie vor leiden viele Patienten unter chemotherapieinduzierter Ubelkeit und Erbrechen (CINV). Dabei lassen sich diese Symptome durch eine leitliniengerechte Prophylaxe weitgehend verhindern, insbesondere, wenn moderne Antiemetika eingesetzt werden.
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