Results 51 to 60 of about 6,120 (193)

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Cardiotoxicidad en una Cohorte de pacientes con Diagnóstico de Cáncer de Mama que Recibieron Quimioterapia con Antraciclinas. Seguimiento a 12 años

Oncología, 2020
Introducción: Los esquemas de quimioterapia en el tratamiento de cáncer de mama incluyen Antraciclinas con una efectividad de respuesta alta, sin embargo en algunos casos el potencial efecto terapéutico se ve limitado por la Cardiomiopatía Inducida por ...
Mayra Patricia Santacruz Maridueña, EDITOR: Dra. Katherine García Matamoros   +1 more
doaj   +1 more source

Gross Agricultural Emissions and Unequal Mitigation Pathways in the Brazilian Legal Amazon: Implications for Climate Justice and the Sustainable Development Goals

Sustainable Development, EarlyView.
ABSTRACT Climate mitigation policies in the Brazilian Legal Amazon have largely focused on aggregate or net emissions, providing limited evidence on how gross agricultural emissions reveal the intensity of productive emission sources independently of carbon removals.
Jorge Eduardo Macedo Simões, Marcelo Bentes Diniz, Márcia Jucá Texeira Diniz, Vanessa da Paixão Alves, Cynthia Simmons   +4 more
wiley   +1 more source

CIPA guide to the patents acts, Paul G. Cole

, 2012
[Review of: CIPA guide to the patents acts, 7th, by Paul G.
Torremans, Paul
core   +7 more sources

Exploring Pain Management for People Living With Dementia in Acute Care Settings Using the COM‐B Framework to Guide Baseline Data Gathering

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To establish a comprehensive pre‐implementation baseline of pain management for people living with dementia (PLWD) in acute hospitals by exploring behavioural, contextual, organisational and clinical practice factors to inform the implementation of the DOTS approach.
Faisal Mahama, Deirdre Harkin, Nicola Hayes, Mandy Doherty, Vivien Coates   +4 more
wiley   +1 more source

Comparación del cribado nutricional CIPA con los nuevos criterios GLIM de desnutrición [PDF]

, 2022
Introducción: La desnutrición es muy frecuente en entornos hospitalarios y se relaciona con una mayor morbimortalidad. En el Hospital Universitario Nuestra Señora de Candelaria se realiza el cribado nutricional CIPA. Recientemente se han publicado los
Guerra Cabrera, Adán Jesús
core  

Case report of a 7-year-old CIPA child with multiple debridement's and amputations.

International Journal of Endorsing Health Science Research, 2021
Background: Congenital Insensitivity to Pain (CIPA), otherwise known as Hereditary Sensory and Autonomic Neuropathy Type IV (HSAN IV), is a rarely occurring autosomal recessive disorder encompassed by a group of hereditary and sensory autonomic ...
Syed Ali Haider Zaidi, Sufyan Razak, Syeda Kiran Fatima, Hafiz Abdul Wase, Syed Mohammad Haider Zaidi, Zeeshan Yousuf, Farah Naz, Bilal Yousuf   +7 more
doaj   +1 more source

New Labor Governance? The German Supply Chain Act and National Governance Mechanisms in Brazil

Regulation &Governance, EarlyView.
ABSTRACT Due diligence laws respond to labor governance challenges and to a lack of public governance addressing human rights violations in Global Value Chains. Despite ongoing contestation, the German Supply Chain Due Diligence Act seeks to hold German‐based firms accountable for human rights risks in their supply chains.
Helena Gräf
wiley   +1 more source

Segurança do trabalho na distribuição do acetileno [PDF]

, 2003
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico. Programa de Pós-Graduação em Engenharia de Produção.A presente pesquisa foi realizada na empresa brasileira White Martins Gases Industriais Ltda, com o objetivo de ...
Centurion, José Marcos Rodrigues
core  

Assessment of an in silico mechanistic model for proarrhythmia risk prediction under the CiPA initiative [PDF]

, 2018
International Council on Harmonization S7B and E14 regulatory guidelines are sensitive but not specific for predicting which drugs are proarrhythmic. In response, the Comprehensive In Vitro Proarrhythmia Assay (CiPA) was proposed that integrates multi ...
Phu N. Tran, Xiaomei Han, Tran, Phu N., Ross H. Johnstone, William J. Crumb, Strauss, David G., Ranolph, Aaron, Wu, Wendy W., Kramer, James, Jiansong Sheng, Li, Zhihua, Crumb, William J., Aaron Randolph, Sheng, Jiansong, Bradley J. Ridder, Wu, Min, Wendy W. Wu, Gary R. Mirams, Johnstone, Ross H., Zhihua Li, David G. Strauss, Kuryshev, Yuri, Wu, Caiyun, Caiyun Wu, Mirams, Gary R., Min Wu, James Kramer, Yuri Kuryshev   +27 more
core   +1 more source