Results 251 to 260 of about 118,307 (297)
Saarvienin A—A Novel Glycopeptide with Potent Activity against Drug‐Resistant Bacteria
A structurally distinct glycopeptide, saarvienin A, represents a new family of glycopeptide antibiotics consisting of five sugar/aminosugar units connected to a halogenated peptide core. Saarvienin A overcomes vancomycin resistance and shows strong activity against drug‐resistant Gram‐positive bacteria, in particular, high‐priority pathogens such as ...
Amninder Kaur+7 more
wiley +2 more sources
A common issue in clinical drug development involves drug–drug interactions (DDI) that may lead to altered drug exposure and subsequent altered safety and efficacy of an investigational drug or concomitant medications (conmeds) in the target patient population.
Alice S. Tang+6 more
wiley +1 more source
Effects of aluminum hydroxide and calcium carbonate antacids on the bioavailability of ciprofloxacin
R. Wayne Frost+4 more
openalex +1 more source
This graphical abstract text can be better represented through illustrations for milk samples, bacteria, risk factors (e.g., handwashing, containers), and antibiotic resistance patterns for clearer understanding and to increase engagement. ABSTRACT Background Staphylococcus aureus (S. aureus) is a versatile pathogen that causes diseases. Raw milk is an
Ahmednur Abdi+2 more
wiley +1 more source
Ciprofloxacin-Induced Allergic Interstitial Nephritis
Rosemarie Helmink+1 more
openalex +1 more source
B Cells as a Host of Persistent Salmonella Typhimurium
B cells: a niche for persistent Salmonella enterica serovar Typhimurium (S. Tm). In vitro, within B cells and in the absence of antibiotics, a persistent population of S. Tm emerges, where the SehA/B gene is implicated. Additionally, a replicative population of S. Tm is also present. Upon antibiotic administration, approximately 90% of the S.
Alonso D. Cruz‐Cruz+4 more
wiley +1 more source
Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota
Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog+8 more
wiley +2 more sources
Oral ciprofloxacin treatment of Pseudomonas aeruginosa osteomyelitis
Michael Dan+3 more
openalex +1 more source
Management of Mycobacterium ulcerans infection (Buruli ulcer) in Australia: consensus statement
Abstract Introduction Buruli ulcer, caused by Mycobacterium ulcerans, is increasing in incidence and spreading to new areas in southeast Australia. With increasing experience and emerging evidence, this consensus statement considers contemporary data to provide up‐to‐date recommendations to clinicians who may encounter this disease.
Stephen Muhi+15 more
wiley +1 more source
Dispersion‐corrected density functional theory (DFT) calculations shed light on the interaction of the anticancer drug 5‐fluorouracil (5‐FU) with a framework‐associated octahedral aluminum site in a FAU‐type zeolite. The calculations help to explain the experimental observation of a limited 5‐FU release from zeolite samples containing such sites ...
Michael Fischer
wiley +1 more source