Results 251 to 260 of about 118,307 (297)

Saarvienin A—A Novel Glycopeptide with Potent Activity against Drug‐Resistant Bacteria

open access: yesAngewandte Chemie, Volume 137, Issue 25, June 17, 2025.
A structurally distinct glycopeptide, saarvienin A, represents a new family of glycopeptide antibiotics consisting of five sugar/aminosugar units connected to a halogenated peptide core. Saarvienin A overcomes vancomycin resistance and shows strong activity against drug‐resistant Gram‐positive bacteria, in particular, high‐priority pathogens such as ...
Amninder Kaur   +7 more
wiley   +2 more sources

Use of Real‐World Claims Data to Assess the Prevalence of Concomitant Medications to Inform Drug–Drug Interaction Risk in Target Patient Populations

open access: yesClinical Pharmacology &Therapeutics, Volume 118, Issue 1, Page 146-155, July 2025.
A common issue in clinical drug development involves drug–drug interactions (DDI) that may lead to altered drug exposure and subsequent altered safety and efficacy of an investigational drug or concomitant medications (conmeds) in the target patient population.
Alice S. Tang   +6 more
wiley   +1 more source

Effects of aluminum hydroxide and calcium carbonate antacids on the bioavailability of ciprofloxacin

open access: green, 1992
R. Wayne Frost   +4 more
openalex   +1 more source

Prevalence, Antimicrobial Susceptibility Pattern and Associated Factors of Staphylococcus Aureus Among Camel's Raw Milk in Babile District, Oromia, Ethiopia

open access: yesVeterinary Medicine and Science, Volume 11, Issue 4, July 2025.
This graphical abstract text can be better represented through illustrations for milk samples, bacteria, risk factors (e.g., handwashing, containers), and antibiotic resistance patterns for clearer understanding and to increase engagement. ABSTRACT Background Staphylococcus aureus (S. aureus) is a versatile pathogen that causes diseases. Raw milk is an
Ahmednur Abdi   +2 more
wiley   +1 more source

Ciprofloxacin-Induced Allergic Interstitial Nephritis

open access: bronze, 1990
Rosemarie Helmink   +1 more
openalex   +1 more source

B Cells as a Host of Persistent Salmonella Typhimurium

open access: yesImmunology, Volume 175, Issue 3, Page 292-299, July 2025.
B cells: a niche for persistent Salmonella enterica serovar Typhimurium (S. Tm). In vitro, within B cells and in the absence of antibiotics, a persistent population of S. Tm emerges, where the SehA/B gene is implicated. Additionally, a replicative population of S. Tm is also present. Upon antibiotic administration, approximately 90% of the S.
Alonso D. Cruz‐Cruz   +4 more
wiley   +1 more source

Antibacterial Siderophores of Pandoraea Pathogens and Their Impact on the Diseased Lung Microbiota

open access: yesAngewandte Chemie, Volume 137, Issue 24, June 10, 2025.
Genome mining of environmental and pathogenic Pandoraea species identified a conserved NRPS gene cluster and led to the discovery of novel siderophores, pandorabactins, which exert their antibacterial activity by depleting iron from competitors. Bioinformatic analysis of sputum from cystic fibrosis patients coupled with bioassays indicates that ...
Elena Herzog   +8 more
wiley   +2 more sources

Oral ciprofloxacin treatment of Pseudomonas aeruginosa osteomyelitis

open access: green, 1990
Michael Dan   +3 more
openalex   +1 more source

Management of Mycobacterium ulcerans infection (Buruli ulcer) in Australia: consensus statement

open access: yesMedical Journal of Australia, Volume 222, Issue 11, Page 571-578, June 2025.
Abstract Introduction Buruli ulcer, caused by Mycobacterium ulcerans, is increasing in incidence and spreading to new areas in southeast Australia. With increasing experience and emerging evidence, this consensus statement considers contemporary data to provide up‐to‐date recommendations to clinicians who may encounter this disease.
Stephen Muhi   +15 more
wiley   +1 more source

Impact of Octahedral Aluminum Sites on Guest Molecule Adsorption in Zeolites: A Computational Study of 5‐Fluorouracil in Zeolite FAU

open access: yesChemistry – A European Journal, Volume 31, Issue 32, June 6, 2025.
Dispersion‐corrected density functional theory (DFT) calculations shed light on the interaction of the anticancer drug 5‐fluorouracil (5‐FU) with a framework‐associated octahedral aluminum site in a FAU‐type zeolite. The calculations help to explain the experimental observation of a limited 5‐FU release from zeolite samples containing such sites ...
Michael Fischer
wiley   +1 more source

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