Results 121 to 130 of about 866,467 (316)

Medical Staff Circle photo

open access: yes
Black and white photo of people, presumably medical staff, sitting in a circle and ...
Modbury Hospital
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Development of motivation for research activities in adolescents in group work

open access: yesРазвитие образования
The work is devoted to the study of the features of development of motivation for research activities in adolescents in club work. Within the framework of research activities, not only the acquisition and comprehension of new knowledge occurs, but also ...
Elena V. Dekina, Kseniya S. Shalaginova
doaj   +1 more source

Circle Solutions, a philosophy and pedagogy for learning positive relationships: What promotes and inhibits sustainable outcomes? [PDF]

open access: yes, 2013
Educators are increasingly aware that the efficacy of social and emotional learning (SEL) is dependent on implementation factors, not just program content.
Sue Roffey   +3 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Estes Embroidery Circle records, MSS.0491

open access: yes, 1928
: Letters, newspaper clippings, meeting minutes, photos, scrapbooks, and diaries of members of this social club in Tuscaloosa, AlabamaScope and Content Note: The collection contains letters, newspaper clippings, meeting minutes, photos, scrapbooks, and ...
Estes Embroidery Circle
core  

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

Developing positive teacher pupil relationships in response to current Chinese educational reform : the potential contribution of circle time [PDF]

open access: yes
This mixed design research sought to introduce, conduct and investigate Circle Time as a pedagogical practice for developing an equal and positive teacher-pupil relationship in a Chinese secondary school and as a contribution to current Chinese ...
Wu, Ling
core  

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