Results 151 to 160 of about 866,467 (316)

Medico Friend Circle Bulletin, 318-319, August-November 2006

Contents: Data Exclusivity: Another Self-Goal and a Trade Barrier S.Srinivasan. Medico Friend Circle Letter to PM on DE. DE in International Trade Agreements. IDMA on DP and DE. Safeguards if Decision by Govt to Introduce DE. On “Unfair Commercial Useâ€
Medico Friend Circle
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Medico Friend Circle Bulletin, August-November 2006, 318-319

Data Exclusivity: Another Self-Goal and a Trade Barrier S.Srinivasan Medico Friend Circle Letter to PM on DE DE in International Trade Agreements IDMA on DP and DE Safeguards if Decision by Govt to Introduce DE On “Unfair Commercial Use†Ricardo and â€
Medico Friend Circle
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Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Eustachian and Aortic Valve Endocarditis: A Rare Case of Concomitant Right- and Left-Sided Endocarditis. [PDF]

Cureus
Riveros Neira N, Behers BJ, Hozayen O, Hamad K, Kraitman N, Wiese-Rometsch W.   +5 more
europepmc   +1 more source

Tomorrow people: countdown to democracy

, 1994
462.B.2.6.pdf created from the media publications in the SA Election material Collection MS 462, held in the Manuscripts Section of the Stellenbosch Library and Information Service.A comic magazine, a joint project by Story Circle and the Centre for ...

core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Atypical variants of the cerebral arterial circle beyond the Lazorthes classification: a retrospective morphologic and neuroradiologic study. [PDF]

Surg Radiol Anat
Bulbuc I, Lupascu M, Bordei P, Ionescu C, Caraban BM.   +4 more
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Large trials of psychosocial interventions: examples from individual placement and support. [PDF]

Int J Public Health
Metcalfe JD, Mueser KT, Drake RE.
europepmc   +1 more source