Results 141 to 150 of about 10,645 (260)

Lacticaseibacillus rhamnosus LRPerfectus158 Alleviates Postinfectious Irritable Bowel Syndrome in Mice and Is Associated With Modulation of Hypothalamic–Pituitary–Adrenal Axis Activity

Food Frontiers, Volume 7, Issue 5, September 2026.
This study demonstrated that administration of Lacticaseibacillus rhamnosus LRPerfectus158 significantly alleviated IBS‐like symptoms in a mouse model by attenuating visceral hypersensitivity, reducing intestinal inflammation, improving epithelial barrier function, and relieving anxiety‐like behaviors.
Dun Su, Yajuan Guo, Yue Wang, Xiaoyue Bai, Guiyuan Yu, Huixian Han, Yizhi Jing, Yuanzhi Yin, Wenjie Chen, Jing Li, Zhengyuan Zhai, Yanling Hao   +11 more
wiley   +1 more source

Mitochondrial DNA mutations are associated with impaired oxidative phosphorylation and enhanced imatinib response in chronic myeloid leukemia

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Mitochondrial DNA (mtDNA) mutations are frequently observed in cancer, but their clinical and functional significance in chronic myeloid leukemia (CML) remains incompletely defined. Here, we show that a distinct mtDNA mutational landscape is associated with mitochondrial metabolic programs and response to imatinib therapy in CML.
Ilaria S. Pagani, Vaidehi Krishnan, John F. Ouyang, Chung H. Kok, BeiJun Chen, Kian Leong Lee, Cong M. Pham, Paul Wang, Elyse Page, Phuong Dang, Verity A. Saunders, Jane James, Kelly Lim, Stefano Mangiola, Yingnan Gao, Naranie Shanmuganathan, Agnes Yong, Susan Branford, Charles Chuah, David T. Yeung, Deborah L. White, Vignir G. Helgason, Daniel Thomas, S. Tiong Ong, Timothy P. Hughes, David M. Ross   +25 more
wiley   +1 more source

Clonotypic characterization defines B‐cell drivers of clonal expansion and intratumor heterogeneity in IgM monoclonal gammopathies

HemaSphere, Volume 10, Issue 9, September 2026.
Abstract Waldenström macroglobulinemia (WM) and IgM monoclonal gammopathy of undetermined significance (MGUS) share the same cell of origin but differ in clonal size. Compared with other B‐cell neoplasms, the lymphoplasmacytic clone in WM can be rather small, limiting our understanding of clonal expansion.
David F. Moreno, Ferran Nadeu, Marta Casado‐Peláez, Caterina Mata, Ian Márquez‐López, Marco A. Fernández, Sergi Vaqué, Elena Medina, Helena Llobregat, Marta Garrote, Joan Mañé, Oriol Cardús, Luis Gerardo Rodríguez‐Lobato, Anna de Daniel, María Teresa Cibeira, Theo Gremen Oliveira, Elizaveta Kulaeva, Ester Lozano, Dolors Colomer, Laura Rosiñol, Ruben van Boxtel, Manel Esteller, Carlos Fernández de Larrea   +22 more
wiley   +1 more source

Chromosome‐level genome and methylome of vine tea suggest roles for tandem duplication and CHH hypomethylation in high dihydromyricetin accumulation

iMetaOmics, Volume 3, Issue 3, September 2026.
A chromosome‐level genome assembly and single‐base resolution methylome of vine tea (Nekemias grossedentata) reveal that lineage‐specific tandem duplications of dihydromyricetin (DHM) biosynthetic genes (NgCHS and NgF3′5′ H) have expanded their copy numbers, providing the genetic basis for high DHM flux.
Yingmei Wu, Hanrui Hu, Qing Ye, Xueqing Chen, Miyuan Tian, Jing Li, Li Lu, Yifei Liu, Yi Shang, Yanling Li, Xingyao Xiong, Junbo Gou   +11 more
wiley   +1 more source

Integration of unpaired and heterogeneous clinical flow cytometry data. [PDF]

iScience
Phuycharoen M, Kaestele V, Williams T, Lin L, Hussell T, Grainger J, CIRCO, Rattray M.   +7 more
europepmc   +1 more source

Establishment of a Real-Time Quantitative PCR Assay for Porcine Circovirus-Like Virus and the First Evidence of Its Spread to Hainan and Jiangxi Provinces of China. [PDF]

Front Vet Sci, 2022
Zhang L, Zhang X, Xu G, Wang L, Liu X, Zhang P, Wang S, Liang T, Wang Z, Liu Y, Xu Z, Li Z, Huang G, Song C.   +13 more
europepmc   +1 more source

Integrative Multi‐Omics Profiling Reveals Age‐Associated Genomic and Tumor Microenvironmental Heterogeneity in Colorectal Cancer

MedComm – Oncology, Volume 5, Issue 3, September 2026.
Integrated multi‐omics analysis defines an age‐resolved molecular–immune framework in colorectal cancer. Early‐onset tumors show reduced APC/KRAS alterations, frequent SMAD4 disruption, enriched PTPRK–RSPO3 fusions, and increased CD4+ memory T cells and mast cells with greater checkpoint responsiveness.
Yang Guo, Yajiao He, Tao Zhou, Haidong Zhang, Fei Liao, Yuelan Wang, Hai‐Ning Chen, Li‐Bin Huang, Xuyang Xia, Yiqi Deng, Jing Wu, Siyu Yang, Heng Xu, Zong‐Guang Zhou, Yang Shu, Lie Yang   +15 more
wiley   +1 more source

B-Cell-Activating Factor (BAFF) Correlated with Serum Vitamin D Values-Possible Markers with a Prognostic Role in Thyroid Autoimmune Diseases. [PDF]

J Clin Med
Musledin Ș, Circo E, Scrinic O.
europepmc   +1 more source

Genome characteristics of atypical porcine pestivirus from abortion cases in Shandong Province, China. [PDF]

Virol J, 2023
Sun X, Zhang Q, Shan H, Cao Z, Huang J.
europepmc   +1 more source

Differential Expression of Human and Bacterial Proteins Reveals Microbiome–Host Crosstalk in Metabolic Disorders

PROTEOMICS – Clinical Applications, Volume 20, Issue 5, September 2026.
ABSTRACT Purpose The growing prevalence of obesity, MetS, and T2DM highlights the need to better understand host–microbiota interactions. While gut microbiota has been widely investigated, interactions between the oral microbiota and human salivary proteins remain largely unexplored.
Carlos Vinicius Ferreira da Silva, Carlos José Ferreira da Silva, Fernanda da Silva Marinho, Youssef Bacila Sade, Sandra Mara Naressi Scapin, Fabiano L. Thompson, Cristiane Thompson, Eidy de Oliveira Santos   +7 more
wiley   +1 more source