Results 41 to 50 of about 10,645 (260)

Circo, Lazer e Esporte: políticas públicas em jogo [PDF]

, 2012
Rede ...
SILVA, Méri Rosane Santos, SILVEIRA, José Francisco Baroni, HECKETHEUER, Luiz Felipe Alcantra   +2 more
core  

Escuela Superior para las Artes Circenses y Teatrales Circo Social, Circo-Técnia, Escuela de Circo

, 2022
In Colombia, the circus and theatrical culture has gained relevance in recent years, especially since 2011 when the project of Law 1493 of 2011 was filed, by which measures were taken to formalize the public entertainment sector, however, said shows they
López Arias, Luis Carlos, Durán Arango, Maria Paula   +1 more
core  

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

Modulating Calcium Homeostasis via a Biomimetic Scaffold to Rescue Diabetic Ischemic Wounds

Advanced Science, EarlyView.
This strategy addresses impaired microcirculation and loss of extracellular matrix (ECM) guidance in diabetic wound healing. Musc@CP, a nanofibrous dressing combining an ECM‐mimetic chitosan‐pullulan scaffold with muscone, enhances perfusion by attenuating intracellular Ca2+ overload‐associated endothelial dysfunction.
Xiang Zheng, Mingmei Li, Jianjun Jiang, Yongchao Wang, Yaru Jia, Weilun Sun, Yi Yao, Pengli Gao, Linhua Zhang, Qi Guo, Guang Jia, Xing‐Jie Liang, Dunwan Zhu, Jinchao Zhang, Fangzhou Li   +14 more
wiley   +1 more source

ENTRE EL “CIRCO CRIOLLO” Y EL “NUEVO CIRCO”: TENSIONES ENTRE LEGITIMACIÓN Y SUBALTERNIDAD EN EL PROCESO DE DESARROLLO CIRCENSE EN ARGENTINA.

Revista Tempos e Espaços em Educação, 2018
En este artículo se presenta una síntesis de la historia del circo en Argentina y a partir de ella, se realizan algunos señalamientos en torno a las diversas construcciones de subalternidad y legitimidad allí evidenciados.
Mariana Lucía Sáez
doaj   +1 more source

Montando e desmontando Quem são e como atuam os riggers circenses?

Arte da Cena, 2021
O circo – com destaque para as modalidades aéreas – vem ganhando espaço no Brasil. São poucas as investigações que analisam o rico e os acidentes no contexto circense de modo que o objetivo foi debater a formação dos responsáveis pela instalação dos ...
João Gabriel Baptistotti Nunes, Marco Antonio Coelho Bortoleto   +1 more
doaj   +1 more source

A High‐Loading Zn Single‐Atom Nanozyme Targets the Zn/HIF‐1α/GLUT1 Axis to Disrupt Glucose Metabolic Reprogramming and Remodel the Tumor Immune Microenvironment

Advanced Science, EarlyView.
A high‐loading Zn single‐atom nanozyme (ZMG@CS) delivers ML‐SA5 and GOx to lysosomes. ML‐SA5 activates TRPML1 to release endogenous Zn2+, while the nanozyme provides exogenous Zn2+ and GOx‐driven acidification amplifies ROS production. Together, these effects suppress the HIF‐1α/GLUT1 axis, disrupt glucose and redox homeostasis, induce disulfidptosis ...
Zhenxin Wang, Yuhang Tang, Ronghao Yue, Jingtao Xu, Yong Tao, Jie Chen, Shipeng Li, Guosheng Zhao, Jinfang Xue, Mingwei Sun, Fenglei Gao, Yunsheng Ou, Yang Wang   +12 more
wiley   +1 more source

Surficial sediment characterization of the Guadiana estuary to evaluate changes in the surface sediments relative to previous analysis within the frame of the CIRCO project

, 2011
CIRCO (2011).
CIRCO Project Members, CIRCO Project Members (8023055)   +1 more
core   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

circZNF148 Drives Glucose Metabolism Reprogramming to Enhance Metastasis and Immune Evasion via HK1 Stabilization in Triple‐Negative Breast Cancer

Advanced Science, EarlyView.
CircZNF148 stabilizes HK1 through deubiquitinase recruitment, thereby enhancing glycolysis and lactate production. Elevated lactate promotes PD‑L1 lactylation and membrane accumulation while suppressing CD8+ T‐cell cytotoxicity, collectively facilitating immune evasion and malignant progression in TNBC.
Yuhan Jin, Wenjing Zhao, Lei Wang, Jianing Wang, Keying Zhao, Dan Luo, Yifei Wang, Yuxia Yang, Jingze Yang, Yaming Li, Tong Chen, Dianwen Han, Zekun Wang, Xiaoyan Li, Bing Chen, Lijuan Wang, Yiran Liang, Qifeng Yang   +17 more
wiley   +1 more source