Results 41 to 50 of about 353,200 (294)

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Mathematical Estimation of Logical Masking Capability of Majority/Minority Gates Used in Nanoelectronic Circuits

open access: yes, 2017
In nanoelectronic circuit synthesis, the majority gate and the inverter form the basic combinational logic primitives. This paper deduces the mathematical formulae to estimate the logical masking capability of majority gates, which are used extensively ...
Balasubramanian, P, Naayagi, R T
core   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

Blackbox Quantization of Superconducting Circuits using exact Impedance Synthesis

open access: yes, 2014
We propose a new quantization method for superconducting electronic circuits involving a Josephson junction device coupled to a linear microwave environment. The method is based on an exact impedance synthesis of the microwave environment considered as a
Abraham, David W.   +2 more
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

A Study of Optimal 4-bit Reversible Toffoli Circuits and Their Synthesis

open access: yes, 2012
Optimal synthesis of reversible functions is a non-trivial problem. One of the major limiting factors in computing such circuits is the sheer number of reversible functions.
Golubitsky, Oleg, Maslov, Dmitri
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Thermoelectric Modules Incorporating MgAgSb and Mg3(Sb,Bi)2 Synthesized Using a Melting Method

open access: yesAdvanced Engineering Materials, EarlyView.
A scalable synthesis method for a thermoelectric material of MgAgSb is established. A thermoelectric power module of MgAgSb/Mg3(Sb,Bi)2 is fabricated, showing the conversion efficiency of 7.4% at ΔT = 315 K. The performance is comparable to conventional Bi2Te3 modules when they are operated with an air‐cooled heat exchanger.
Kazuo Nagase   +8 more
wiley   +1 more source

Multitask Evolution with Cartesian Genetic Programming

open access: yes, 2017
We introduce a genetic programming method for solving multiple Boolean circuit synthesis tasks simultaneously. This allows us to solve a set of elementary logic functions twice as easily as with a direct, single-task approach.Comment: 2 ...
Caruana Rich   +2 more
core   +1 more source

On the suitability and development of layout templates for analog layout reuse and layout-aware synthesis [PDF]

open access: yes, 2005
Accelerating the synthesis of increasingly complex analog integrated circuits is key to bridge the widening gap between what we can integrate and what we can design while meeting ever-tightening time-to-market constraints.
Castro López, Rafael   +2 more
core   +1 more source

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