Results 121 to 130 of about 5,709,499 (335)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Prediction of subsonic vortex shedding from forebodies with chines [PDF]

open access: yes
An engineering prediction method and associated computer code VTXCHN to predict nose vortex shedding from circular and noncircular forebodies with sharp chine edges in subsonic flow at angles of attack and roll are presented.
Lesieutre, Daniel J.   +1 more
core   +1 more source

Exotic Hill Problem: Hall motions and symmetries

open access: yes, 2012
Our previous study of a system of bodies assumed to move along almost circular orbits around a central mass, approximately described by Hill's equations, is extended to "exotic" [alias non-commutative] particles.
D. Heggie   +8 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Prediction of vortex shedding from circular and noncircular bodies in subsonic flow [PDF]

open access: yes
An engineering prediction method and associated computer code VTXCLD are presented which predict nose vortex shedding from circular and noncircular bodies in subsonic flow at angles of attack and roll.
Lesieutre, Daniel J.   +1 more
core   +1 more source

Circular 03/07 : school sixth form reviews : managing proposals for change [PDF]

open access: yes, 2003
"The Learning and Skills Council (LSC) shares responsibility for the planning of sixth form provision in schools with local education authorities, governing bodies, Church authorities and other faith groups.

core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Structure of Saturn's rings: Optical and dynamical considerations [PDF]

open access: yes
The photometric phase curves of Saturn's rings are considered, as well as a conflict between dynamical and photometric models of the rings. The dependence of ring brightness on angular separation of the earth and sun as viewed from Saturn is discussed ...
Franklin, F. A.
core   +1 more source

Periodic solutions for circular restricted \(N+1\)-body problems

open access: yes, 2013
Summary: For circular restricted \(N+1\)-body problems, we study the motion of a sufficiently small mass point (called the zero mass point) in the plane of \(N\) equal masses located at the vertices of a regular polygon. By using variational minimizing methods, for some \(N\), we prove the existence of the noncollision periodic solution for the zero ...
Zhao, Xiaoxiao, Li, Wei, Wang, Peng
openaire   +2 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

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