Results 41 to 50 of about 98,250 (261)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Investigation of New Tsallis-Based Equation to Predict Shear Stress Distribution in Circular and Trapezoidal Channels

Entropy, 2019
In this study, the entropy concept is employed to estimate the shear stress distribution in a circular channel with flat bed and trapezoidal channel.
Zohreh Sheikh Khozani, Wan Hanna Melini Wan Mohtar   +1 more
doaj   +1 more source

Finite Element Analysis of Air Flow and Temperature Distribution on Surface of a Circular Obstacle with Resistance and Orientation of Screen

Journal of Mathematics, 2021
Nonisothermal flow through the rectangular channel on a circular surface under the influence of a screen embedded at the middle of a channel at angles θ is considered.
Abid A. Memon, M. Asif Memon, Aisha M. Alqahtani, Kaleemullah Bhatti, Kamsing Nonlaopon, Ilyas Khan, Mulugeta Andualem   +6 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Random pore structure and REV scale flow analysis of engine particulate filter based on LBM

Open Physics, 2020
In this article, lattice Boltzmann method (LBM) is used to simulate the multi-scale flow characteristics of the engine particulate filter at the pore scale and the representative elementary volume (REV) scale, respectively. Four kinds of random wall-pore
Wu Chunrui, Zhang Tiechen, Fu Jiale, Liu Xiaori, Shen Boxiong   +4 more
doaj   +1 more source

Capturing individual charged microparticles and cells with microelectrodes in a circular microfluidic channel

AIP Advances, 2022
Capture and, subsequently, in situ characterization of microparticles generally require complex fabrication processes and sophisticated techniques in microfluidic devices.
Mingyan Wang, Li Zhou, Zhi Qi
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Channel Shape Effects on Device Instability of Amorphous Indium–Gallium–Zinc Oxide Thin Film Transistors

Micromachines, 2020
Channel shape dependency on device instability for amorphous indium–gallium–zinc oxide (a-IGZO) thin film transistors (TFTs) is investigated by using various channel shape devices along with systematic electrical characterization including DC I-V ...
Seung Gi Seo, Seung Jae Yu, Seung Yeob Kim, Jinheon Jeong, Sung Hun Jin   +4 more
doaj   +1 more source

Intersymbol Interference for Electrophoretic Molecular Communication in Circular Duct Channels

IEEE Communications Letters, 2022
This paper investigates electrophoretic molecular communication (EMC) operating in circular duct channels. EMC utilizes the time-varying electrophoretic force that can controllably induce the movement of charged particles to enhance communication performance.
Sunghwan Cho, Justin P. Coon, Thomas C. Sykes, Alfonso A. Castrejón-Pita   +3 more
openaire   +2 more sources

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source