Results 101 to 110 of about 3,020,470 (372)

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Functions of Circular RNA in Human Diseases and Illnesses

open access: yesNon-Coding RNA, 2023
Circular RNAs (circRNAs) represent single-stranded RNA species that contain covalently closed 3′ and 5′ ends that provide them more stability than linear RNA, which has free ends.
Alison Gu   +5 more
doaj   +1 more source

Electrostatic contribution to DNA condensation - application of 'energy minimization' in a simple model in strong Coulomb coupling regime

open access: yes, 2011
Bending of DNA from a straight rod to a circular form in presence of any of the mono-, di-, tri- or tetravalent counterions has been simulated in strong Coulomb coupling environment employing a previously developed energy minimization simulation ...
Arup K Mukherjee   +5 more
core   +1 more source

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

open access: yesFEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt   +4 more
wiley   +1 more source

TempliPhi, ⌽29 DNA Polymerase Based Rolling Circle Amplification of Templates for DNA Sequencing

open access: yesBioTechniques, 2002
We have developed a novel, isothermal DNA amplification strategy that employs ⌽29 DNA polymerase and rolling circle amplification to generate high-quality templates for DNA sequencing reactions. The TempliPhi™ DNA amplification kits take advantage of the
John R. Nelson   +10 more
doaj   +1 more source

Determination of plasmid copy number in yeast transformants by means of agarose plugs [PDF]

open access: yes, 1993
The determination of plasmid copy number in Saccharomyces cerevisiaetransformants containing circular or linear plasmids is currently performed with total yeast DNA extracts obtained from cultures grown under selection.
AM Guerrini   +3 more
core   +1 more source

Conformations of Circular DNA

open access: yes, 1997
5 pages, 3 figures using epsf.tex ...
Fain, Boris, Rudnick, Joseph
openaire   +2 more sources

Circular dichroism and conformational polymorphism of DNA [PDF]

open access: yesNucleic Acids Research, 2009
Here we review studies that provided important information about conformational properties of DNA using circular dichroic (CD) spectroscopy. The conformational properties include the B-family of structures, A-form, Z-form, guanine quadruplexes, cytosine quadruplexes, triplexes and other less characterized structures.
Jaroslav Kypr   +3 more
openaire   +3 more sources

Evolutionary interplay between viruses and R‐loops

open access: yesFEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi   +4 more
wiley   +1 more source

Virological and morphological relationships in the phases of the immune control and reactivation in patients with chronic hepatitis B

open access: yesЖурнал инфектологии, 2016
Objective: To evaluate relationships between virological and morphological data in patients with chronic hepatitis B in phase immune control and reactivation.Materials and methods: The study involved 46 patients with chronic hepatitis B, indicators ...
I. A. Gabdrakhmanov   +12 more
doaj   +1 more source

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