Results 271 to 280 of about 3,020,470 (372)
The glomerular filtration barrier (GFB) is the first step of blood filtration by the kidneys. The concerning increase of kidney diseases makes the development of new models essential. In this context, microphysiological glomerular filtration barriers focus on closely reproducing the physiological architecture of the in vivo GFB: podocytes, glomerular ...
Manon Miran+5 more
wiley +1 more source
Correction to 'Molecular mechanisms of extrachromosomal circular DNA formation'. [PDF]
europepmc +1 more source
VAV2 exists in extrachromosomal circular DNA and contributes Enzalutamide resistance of prostate cancer via stabilization of AR/ARv7. [PDF]
Wang Q+13 more
europepmc +1 more source
Viscometric analysis of the interaction of bisphenanthridinium compounds with closed circular supercoiled and linear DNA [PDF]
W. David Wilson+3 more
openalex +1 more source
Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez+3 more
wiley +1 more source
Decoding the genomic enigma: Approaches to studying extrachromosomal circular DNA. [PDF]
Yuan XQ+9 more
europepmc +1 more source
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Identification and Characterization of Extrachromosomal Circular DNA in Slimming Grass Carp. [PDF]
He H+7 more
europepmc +1 more source