Results 331 to 340 of about 3,020,470 (372)

Comparative Analysis of Active LTR Retrotransposons in Sunflower (Helianthus annuus L.): From Extrachromosomal Circular DNA Detection to Protein Structure Prediction. [PDF]

Int J Mol Sci
Kazancev M, Merkulov P, Tiurin K, Demurin Y, Soloviev A, Kirov I.   +5 more
europepmc   +1 more source

Embedded 3D‐Coaxial Bioprinting of Stenotic Brain Vessels with a Mechanically Enhanced Extracellular Matrix Bioink for Investigating Hemodynamic Force‐Induced Endothelial Responses

Advanced Functional Materials, EarlyView.
In this study, a physically enhanced vascular dECM bioink and used 3D‐coaxial bioprinting are developed to fabricate mature brain blood vessels for cerebral atherosclerosis research. This model demonstrates that vascular geometry‐induced hemodynamic changes trigger vascular inflammation, ensuring its potential for cerebrovascular research.
Wonbin Park, Min‐Ju Choi, Jae‐Seong Lee, Minjun Ahn, Wonil Han, Ge Gao, Dong‐Woo Cho, Byoung Soo Kim   +7 more
wiley   +1 more source

Extrachromosomal circular DNA containing DTX1 promotes cell growth in hydroquinone-induced malignantly transformed cells by regulating the transcription of DTX1. [PDF]

BMC Cancer
Ling X, Jiao Q, Lin D, Chen J, Han Y, Meng J, Zhong B, Zhang H, Zhang G, Zhu F, Qin J, Ruan Y, Liu L.   +12 more
europepmc   +1 more source

Synthetic Strategy for mRNA Encapsulation and Gene Delivery with Nanoscale Metal‐Organic Frameworks

Advanced Functional Materials, EarlyView.
This research utilizes the ZIF‐8 for the encapsulation and intracellular delivery of nucleic acids, specifically mRNA, for applications in gene delivery. Integrating PEI addresses the issue of mRNA leakage from ZIF‐8, resulting in the delivery and expression of green fluorescent protein (GFP) in vitro and firefly luciferase in vivo.
Harrison Douglas Lawson, Huy Hoang Nguyen, Keng‐Jung Lee, Nattarat Wongsuwan, Ayesha Tupe, Mengrou Lu, Mariah Lynn Arral, Anne Behre, Zihan Ling, Kathryn Ann Whitehead, Adam Walter Feinberg, Xi Ren, Si‐Yang Zheng   +12 more
wiley   +1 more source

Beyond the Chromosome: Recent Developments in Decoding the Significance of Extrachromosomal Circular DNA (eccDNA) in Human Malignancies. [PDF]

Life (Basel)
Tsiakanikas P, Athanasopoulou K, Darioti IA, Agiassoti VT, Theocharis S, Scorilas A, Adamopoulos PG.   +6 more
europepmc   +1 more source

Differential Compartmentalization of Enzymatic Reactions for Lactate Signaling Across Protocells

Advanced Functional Materials, EarlyView.
Two populations of protocells consisting of giant unilamellar vesicles containing active species and distinct artificial organelles are competent of collective behavior by mimicking production, intercellular communication, and detection of the bioinspired signal molecule lactate. Enzymatic cascade reactions within artificial organelles demonstrate that
Arianna Balestri, Xinan Huang, Emanuel Lörtscher, Cora‐Ann Schoenenberger, Cornelia G. Palivan   +4 more
wiley   +1 more source

Extrachromosomal circular DNA and their roles in cancer progression. [PDF]

Genes Dis
Zheng S, Li Y, Wang L, Wei Q, Wei M, Yu T, Zhao L.   +6 more
europepmc   +1 more source

A Sustainable Biotechnology Approach for Mineral Separation

Advanced Functional Materials, EarlyView.
Silver‑binding peptides are first identified through phage‐display screening, and then engineered into multifunctional and responsive peptides or proteins. These tailored biomolecules can selectively capture and aggregate silver particles or ions from complex mixtures, enabling rapid and efficient silver separation and recovery.
Guangze Yang, Yun Liu, Shankar Raj Devkota, Yue Hui, Ruilin Zhao, Yang Li, David A. Weitz, Chun‐Xia Zhao   +7 more
wiley   +1 more source

Glutamate dehydrogenase 1-dependent α-ketoglutarate promotes hepatitis B virus transcription by modulating histone methylations on the covalently closed circular DNA minichromosome. [PDF]

Clin Mol Hepatol
Cheng ST, Chen WX, Deng HJ, He X, Zhang H, Tan M, Yu HB, Zhang ZZ, Ren JH, Yang ML, Zhang DP, Li ZH, Chen J.   +12 more
europepmc   +1 more source

Endocytic Programming via Porous Silicon Nanoparticles Enhances TLR4 Nanoagonist Potency for Macrophage‐Mediated Immunotherapy

Advanced Functional Materials, EarlyView.
Porous silicon nanoparticles (PSiNPs) reprogram macrophage endocytosis of manganese@albumin‐based TLR4 nanoagonists, driving TRIF‐biased TLR4 signaling, eliciting robust proinflammatory responses, and potentiating macrophage‐mediated immunotherapeutic effects against NSCLC.
Xiaomei Zhang, Huiying Li, Shuodan Huang, Linxuan Zhang, Yan Gao, Ruoran Wang, Xiaoyu Wang, Hélder A. Santos, Zhenyu Yin, Bing Xia   +9 more
wiley   +1 more source