Results 41 to 50 of about 3,020,470 (372)

Rapid Turnover of Hepatitis B Virus Covalently Closed Circular DNA Indicated by Monitoring Emergence and Reversion of Signature‐Mutation in Treated Chronic Hepatitis B Patients

open access: yesHepatology, 2020
Hepatitis B virus (HBV) covalently closed circular DNA (cccDNA) plays a pivotal role in the establishment and persistence of HBV infection. Understanding the turnover time of preexisting cccDNA pools would be helpful in designing strategies to clear HBV ...
Qi Huang   +10 more
semanticscholar   +1 more source

Statistical analysis on detecting recombination sites in DNA-beta satellites associated with the old world geminiviruses [PDF]

open access: yes, 2010
Although an exchange of genetic information by recombination plays an important role in the evolution of viruses, it is not clear how it generates diversity.
Xu, Kai, Yoshida, Ruriko
core   +4 more sources

Exploiting circular DNA [PDF]

open access: yesProceedings of the National Academy of Sciences, 1998
Using circular DNA to measure the degree of unwinding of the double helix caused by ligand binding was one of the first applications of the specific properties of circular DNA. The approach is conceptually simple. Consider a nicked circular DNA of N base pairs that is bound to molecules of a ligand so that the ratio of bound ligands to base pairs is ...
openaire   +3 more sources

BmCPV-Derived Circular DNA vcDNA-S7 Mediated by Bombyx mori Reverse Transcriptase (RT) Regulates BmCPV Infection

open access: yesFrontiers in Immunology, 2022
Circular DNAs derived from single-stranded RNA viruses play important roles in counteracting viral infection. However, whether double-stranded RNA viruses generate functional circular DNAs is still unknown. Using circDNA sequencing, divergent PCR, DNA in
Min Zhu   +13 more
doaj   +1 more source

Circular mitochondrial DNA: A Geant4-DNA user application for evaluating radiation-induced damage in circular mitochondrial DNA

open access: yesJournal of Medical Signals and Sensors, 2017
Background: The aim of this study was to develop a nucleotide geometrical model of the circular mitochondrial DNA (mt-DNA) structure using Geant4-DNA toolkit to predict the radiation-induced damages such as single-strand breaks (SSB), double-strand ...
Mohammad Bagher Tavakoli   +3 more
doaj   +1 more source

Small Circular DNA Molecules as Triangular Scaffolds for the Growth of 3D Single Crystals

open access: yesBiomolecules, 2020
DNA is a very useful molecule for the programmed self-assembly of 3D (three dimension) nanoscale structures. The organised 3D DNA assemblies and crystals enable scientists to conduct studies for many applications such as enzymatic catalysis, biological ...
Yu Wang   +4 more
doaj   +1 more source

Construction of DNA hemicatenanes from two small circular DNA molecules. [PDF]

open access: yesPLoS ONE, 2015
DNA hemicatenanes, one of the simplest possible junctions between two double stranded DNA molecules, have frequently been mentioned in the literature for their possible function in DNA replication, recombination, repair, and organization in chromosomes ...
Claire Gaillard, François Strauss
doaj   +1 more source

Circular DNA elements of chromosomal origin are common in healthy human somatic tissue

open access: yesNature Communications, 2018
The human genome is generally organized into stable chromosomes, and only tumor cells are known to accumulate kilobase (kb)-sized extrachromosomal circular DNA elements (eccDNAs).
Henrik D. Møller   +11 more
semanticscholar   +1 more source

Efficient Arrangement of the Replication Fork Trap for In Vitro Propagation of Monomeric Circular DNA in the Chromosome-Replication Cycle Reaction

open access: yesLife, 2018
Propagation of genetic information is a fundamental prerequisite for living cells. We recently developed the replication cycle reaction (RCR), an in vitro reaction for circular DNA propagation, by reconstitution of the replication cycle of the ...
Tomonori Hasebe   +3 more
doaj   +1 more source

Analysis of a circular code model [PDF]

open access: yes, 2001
A circular code has been identified in the protein (coding) genes of both eukaryotes and prokaryotes by using a statistical method called Trinucleotide Frequency method (TF method) [Arquès & Michel, (1996) J.Theor. Biol. 182, 45-58].
Lacan, Jérôme, Michel, Christian
core   +1 more source

Home - About - Disclaimer - Privacy