Results 181 to 190 of about 1,797,821 (330)

Circular RNA: An emerging frontier in RNA therapeutic targets, RNA therapeutics, and mRNA vaccines.

Journal of Controlled Release, 2022
Xiang Liu, Yu Zhang, Shurong Zhou, Lauren Dain, Lei Mei, G. Zhu   +5 more
semanticscholar   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

CircNet: a database of circular RNAs derived from transcriptome sequencing data [PDF]

, 2015
Yu‐Chen Liu, Jianrong Li, Chuan-Hu Sun, Erik Andrews, Rou-Fang Chao, Feng-Mao Lin, Shun-Long Weng, Sheng‐Da Hsu, Chieh‐Chen Huang, Chao Cheng, Chun-Chi Liu, Hsien‐Da Huang   +11 more
openalex   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Circular RNA expression in ALS is progressively deregulated and tissue-dependent. [PDF]

BMC Genomics
Moreno-García L, Moreno-Martínez L, de la Torre M, Macías-Redondo S, García-Redondo A, Osta R, Toivonen JM, Calvo AC.   +7 more
europepmc   +1 more source

Faculty Opinions recommendation of Circular RNAs are the predominant transcript isoform from hundreds of human genes in diverse cell types.

, 2012
Steven L. Salzberg
openalex   +2 more sources

LIN28B Promotes Cancer Cell Dissemination and Angiogenesis

Advanced Biology, EarlyView.
Children diagnosed with high‐risk neuroblastoma have a 5‐year event‐free survival rate of less than 50% and poor outcomes after recurrence. Deregulation of the LIN28B oncogene can be addressed in these patients. Upregulation of LIN28B is shown to support the metastatic cascade.
Diana Corallo, Sara Menegazzo, Marcella Pantile, Silvia Bresolin, Carlo Zanon, Alessandro Davini, Massimiliano Mazzone, Alessandra Biffi, Sanja Aveic   +8 more
wiley   +1 more source

Enhancement of CRISPR-Cas12a system through universal circular RNA design. [PDF]

Cell Rep Methods
Wang J, Zhang W, Li W, Xie Q, Zang Z, Liu C.   +5 more
europepmc   +1 more source

HMGB1 Derived from the Pyroptotic Microenvironment Promotes Macrophage Extracellular Traps in Hirschsprung‐Associated Enterocolitis

Advanced Biology, EarlyView.
HMGB1 derived from the pyroptotic environment in Hirschsprung‐associated enterocolitis mediates the formation of macrophage extracellular traps through TLR4 ‐p38 MAPK/p65 NF‐kB signaling pathways. Macrophage extracellular traps induce increased ROS production and pyroptosis of colonic epithelial cells.
Rui Zhang, Jing Li, Lili Song, Liya Pan, Chengchen Zhang, Zhiyan Zhan, Li Hong   +6 more
wiley   +1 more source

The Role of Circular RNA in the Progression of Gliomas and Its Potential Clinical Applications. [PDF]

Biology (Basel)
Wu W, Xiong M, Jiang C, Zhou X, Ma Y, Wang T, He S, Ma B.   +7 more
europepmc   +1 more source