Results 201 to 210 of about 1,797,821 (330)

Intersection Between Local Anesthetics and Cancer Biology: What Now? Where Are We Going?

Advanced Biology, EarlyView.
Local anesthetics (LAs), widely used in anesthesia, may also play a role in cancer treatment by inhibiting tumor growth, reducing metastasis, and enhancing immune responses. They modulate key pathways like AKT/mTOR and RAS/ERK while affecting angiogenesis and tumor innervation and the immune response.
Eduardo Nunez‐Rodriguez, Hao Zhang, Dhananjay Sah, Juan P. Cata   +3 more
wiley   +1 more source

CircSeqAlignTk: An R package for end-to-end analysis of RNA-seq data for circular genomes [version 2; peer review: 1 approved, 2 approved with reservations]

F1000Research
RNA sequencing (RNA-seq) technology has become one of the standard tools for studying biological mechanisms at the transcriptome level. Advances in RNA-seq technology have led to the development of numerous publicly available tools for RNA-seq data ...
Wei Cao, Jianqiang Sun, Xi Fu
doaj  

Development and comprehensive evaluation of scarless circularization systems for circular RNA therapeutics. [PDF]

Mol Ther Nucleic Acids
Chen L, Song L, Yang J, Li T, Ju R, Sun C, Xie Z.   +6 more
europepmc   +1 more source

Circular RNA identification based on multiple seed matching

Briefings Bioinform., 2018
Yuan Gao, Jinyang Zhang, F. Zhao
semanticscholar   +1 more source

Investigating the Cellular Effects of GALC Dosing in Enzyme Replacement Therapy for Krabbe Disease Supports the Role of Nanomedicine

Advanced Biology, EarlyView.
A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso, Sara Carpi, Laura Colagiorgio, Miriam De Sarlo, Mariacristina Gagliardi, Marco Cecchini   +5 more
wiley   +1 more source

Protocol for accurately annotating circular RNA and microRNA in giant vertebrate genomes. [PDF]

STAR Protoc
Mishra K.
europepmc   +1 more source

Metazoan tRNA introns generate stable circular RNAs in vivo

, 2015
Zhipeng Lü, Grigory S. Filonov, John J. Noto, Casey A. Schmidt, Talia Hatkevich, Ying Wen, Samie R. Jaffrey, A. Gregory Matera   +7 more
openalex   +2 more sources

Identification of senescence-associated circular RNAs (SAC-RNAs) reveals senescence suppressor CircPVT1 [PDF]

, 2016
Amaresh C. Panda, Ioannis Grammatikakis, Kyoung Mi Kim, Supriyo De, Jennifer L. Martindale, Rachel Munk, Xiaoling Yang, Kotb Abdelmohsen, Myriam Gorospe   +8 more
openalex   +1 more source

Consolidate Overview of Ribonucleic Acid Molecular Dynamics: From Molecular Movements to Material Innovations

Advanced Engineering Materials, EarlyView.
Molecular dynamics simulations are advancing the study of ribonucleic acid (RNA) and RNA‐conjugated molecules. These developments include improvements in force fields, long‐timescale dynamics, and coarse‐grained models, addressing limitations and refining methods.
Kanchan Yadav, Iksoo Jang, Jong Bum Lee
wiley   +1 more source

RNA PolyA Tailing Assay to Qualitatively Analyze Circular RNA Manufacturing. [PDF]

Bio Protoc
Chuang ZS, Su CI, Wang HI, Yu CY.
europepmc   +1 more source