Results 171 to 180 of about 9,296 (290)

A Real‐Time Antifouling Multivalent Aptamer Platform for Wash‐Free Electrochemical Detection of Low‐Abundance Biomarkers in Human Plasma

open access: yesAngewandte Chemie, EarlyView.
Detection of low‐abundance proteins at the point‐of‐care is key for early detection and real‐time monitoring. The clinical translation of such assays is hindered by biofouling, matrix variability, and signal instability. RT‐MagMAp assay overcomes these challenges and enables precise protein quantification in human plasma using a hierarchical assembly ...
Payel Sen   +8 more
wiley   +2 more sources

Intensity-asymmetric wavefront shaping in nonlocal meta-lens. [PDF]

open access: yesNat Commun
Yao J   +8 more
europepmc   +1 more source

One‐step generation of heritable mitochondrial DNA multiplex‐engineered rats using DddA‐derived cytosine base editor

open access: yesAnimal Models and Experimental Medicine, EarlyView.
We established that mixed DdCBE microinjection is an efficient, heritable, and precise strategy for generating multiplex mtDNA mutant rats. This advancement significantly expands the utility of DdCBEs for mitochondrial disease modeling, providing a robust platform for exploring the pathogenic mechanisms of complex mtDNA mutations and developing ...
Xu Zhang   +14 more
wiley   +1 more source

Confined B‐Cell Reconstruction and High T‐Cell Clonality Define Clinical Response to Cladribine Treatment

open access: yesAnnals of Neurology, EarlyView.
Cladribine tablets are approved for relapsing multiple sclerosis, mediating their clinical effect by moderately depleting lymphocytes. In a prospective, monocentric study including 22 patients completing 2 annual cycles of cladribine, B‐ and T‐cell receptor repertoires and relapse activity were assessed at baseline and after 24 months. T‐cell clonality
Tilman Schneider‐Hohendorf   +8 more
wiley   +1 more source

Machine learning-optimized compact wearable frequency reconfigurable antenna for sub-6 GHz/mm-wave 5G integration. [PDF]

open access: yesSci Rep
Salisu A   +8 more
europepmc   +1 more source

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