Results 131 to 140 of about 949,261 (229)

Untargeted Metabolomics Identifies N‐Lactoyl‐Amino Acids as Dose‐Responsive Plasma Biomarkers of Metformin Adherence in Type 2 Diabetes

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 1057-1069, April 2026.
Metformin is the most widely prescribed antidiabetic drug, yet adherence remains difficult to objectively assess. Using untargeted metabolomics and lipidomics, we analyzed plasma from 637 patients with type 2 diabetes (T2D) with confirmed metformin use and 143 nondiabetic controls, annotating 614 metabolites.
Tomas Cajka   +12 more
wiley   +1 more source

ASL 4D MRA Intracranial Vessel Segmentation With Deep Learning U‐Nets

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 4, Page 2384-2396, April 2026.
ABSTRACT Purpose To propose a spatio‐temporal U‐Net based network (4DST) that exploits both spatial and dynamic information while avoiding memory‐intensive 4D convolutional layers for ASL‐based non‐contrast enhanced 4‐dimensional MR angiography (4D MRA) vessel segmentation.
Sang Hun Chung   +7 more
wiley   +1 more source

Bilateral Transcranial Doppler Monitoring During Neonatal Cardiac Surgery; Guidance for Clinical and Scientific Use

open access: yesPediatric Anesthesia, Volume 36, Issue 4, Page 370-378, April 2026.
ABSTRACT Introduction Neonates undergoing cardiac surgery face a high risk of neurological injury and neurodevelopmental complications. Transcranial Doppler monitoring is used and validated in adults to measure cerebral blood flow and can provide valuable insights into cerebral perfusion in neonates.
B. V. Martherus   +11 more
wiley   +1 more source

Using phase-contrast MRI to assist in assessment of shunt function following postoperative intraventricular hemorrhage: illustrative case. [PDF]

open access: yesJ Neurosurg Case Lessons
Ha JH   +17 more
europepmc   +1 more source

Remembering Courtney Cazden, 1925–2025

open access: yesReading Research Quarterly, Volume 61, Issue 2, April/May/June 2026.
ABSTRACT Here we remember and honor Courtney B. Cazden (1925–2025), whose scholarship, mentorship, and moral clarity profoundly shaped the study of language, literacy, and learning. Drawing on our shared experiences as colleagues, collaborators, students, and friends, we reflect on Courtney's enduring contributions to classroom discourse analysis ...
Kris D. Gutiérrez   +5 more
wiley   +1 more source

Radiological Loco‐Regional Treatments for Cholangiocarcinoma: A Systematic Review of the Literature

open access: yesLiver International, Volume 46, Issue 4, April 2026.
ABSTRACT Cholangiocarcinoma (CCA) is the second most common primary liver cancer and is being diagnosed with increasing frequency worldwide. We performed a systematic review on radiofrequency (RFA), microwave (MWA), irreversible electroporation (IRE), trans‐arterial chemoembolization (TACE) and selective internal radiation therapy (SIRT) in CCA. Thirty‐
Dimitrios Pallas   +6 more
wiley   +1 more source

α‐Adrenergic blockade impairs ductus venosus shunting during an acute period of fetal hypoxaemia without further deficits to cerebral oxygen delivery

open access: yesExperimental Physiology, Volume 111, Issue 4, Page 1796-1807, 1 April 2026.
Abstract The fetal circulation has unique shunts, including the ductus venosus (DV), the tone of which dictates how much substrate‐rich blood returning from the placenta is streamed preferentially away from the liver and instead towards the heart. Herein, we aimed to use clinically relevant MRI techniques in sheep to measure indirectly induced changes ...
Jack R. T. Darby   +6 more
wiley   +1 more source

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