Targeting a nucleotide‐sensitive groove on Hsp70 that binds the Bim BH3 helix, we integrate structures, biophysics, and SAR from peptides, fragments, and phenalene‐dicarbonitrile “wedges.” These disrupt the Hsp70–Bim complex with sub‐µM cellular engagement and in vivo activity while sparing Hsp90/mortalin.
Emadeldin M. Kamel +5 more
wiley +1 more source
Comparison of Stoma Formation Using Circular Stapler Fascial-Aperture Technique (Stapled Trephination) Versus the Traditional Method (Cruciate Fascial Incision): A Retrospective Study at King Faisal Specialist Hospital. [PDF]
Afasha K +5 more
europepmc +1 more source
Correction: The impact of powered circular staplers on anastomotic leak in left-sided colorectal cancer surgeries [PDF]
Hayoung Lee +8 more
openalex +1 more source
Abstract Integrating diverse trees and shrubs (hereafter ‘trees’) in agricultural landscapes has emerged as a crucial nature‐based solution to the triple challenge of biodiversity loss, climate change and food security. The potential benefits of on‐farm trees for both people and nature, however, are often constrained by inadequate consideration of ...
Ennia Bosshard +6 more
wiley +1 more source
Usefulness of a powered circular stapler compared with a manual circular stapler in patients undergoing colorectal cancer surgery: A retrospective cohort study and systematic review. [PDF]
Mizumoto R +14 more
europepmc +1 more source
Mechanical hepaticojejunostomy: can we use a circular stapler as a viable and safe alternative? -a retrospective study of a single center. [PDF]
Fabbri N +6 more
europepmc +1 more source
Abstract Tree‐planting initiatives are a crucial part of international sustainability and climate action efforts. Yet, many of these initiatives fail to achieve their long‐term sustainability and climate goals. The role of community value is an often‐overlooked factor in promoting the success of new tree plantings.
Claire L. Narraway +8 more
wiley +1 more source
Comparison of standard circular stapler anastomosis with or without circumferential suture enhancement in patients with robot-assisted Ivor-Lewis oesophagectomy due to malignant tumours of the oesophagus and oesophagogastric junction-a multi-centre, randomised, superiority study (STITCHES). [PDF]
Hinkelmann J +7 more
europepmc +1 more source
Study flow diagram-Double circular stapler technique (DCST).
Claudio Peixoto Crispi Jr (21192258) +7 more
openalex +1 more source

