Results 121 to 130 of about 22,403 (300)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

PRÁTICAS CIRCULARES NA VIOLÊNCIA DOMÉSTICA: TERAPIA E RECONCILIAÇÃO

Direito Público, 2020
Este artigo analisa criticamente o Guia de Práticas Circulares que orienta a aplicação da justiça restaurativa em casos de violência doméstica. Argumentamos que o guia centra-se em práticas míticas e místicas na busca do eu verdadeiro e da cura ...
Carmen Hein De Campos, Jacqueline Padão
doaj  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Cameron Lesions With Severe Anemia: A Case Report. [PDF]

Cureus, 2023
Rajaram-Gilkes M, Cardona JJ, Gilkes AJ.
europepmc   +1 more source

Las normas administrativas y el sistema de fuentes

Revista de Derecho (Coquimbo), 2015
En esta investigación se analiza, desde una perspectiva general, la naturaleza, fundamentos y efectos de las diversas normas que emanan de los órganos de la Administración del Estado, con el objeto de establecer un marco general para comprender la forma
Eduardo Cordero Quinzacara
doaj  

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Carpeta que contiene las circulares diocesanas

, 2012
Carpeta que contiene las circulares diocesanas, 1961 ...
Parroquia de la Inmaculada Concepción de Tepecoacuilco (author)
core  

NGL supersonic separator: modeling, improvement, and validation and adjustment of k-epsilon RNG modified for swirl flow turbulence model

Revista Facultad de Ingeniería Universidad de Antioquia, 2017
CFD, procesamiEl procesamiento de gas natural requiere la aplicación de nuevas tecnologías en un contexto de aumento de la demanda en todo el mundo. La separación de líquidos de gas natural (LGN) utilizando dispositivos supersónicos, es una novedosa y ...
Marco Andrés Guevara-Luna, Luis Carlos Belalcázar-Cerón   +1 more
doaj