Results 211 to 220 of about 9,752 (258)

A Dual‐Phase Exosomal Nanotherapy Enhances Continual Efferocytosis by Coordinating Checkpoint Inhibition and Metabolic Reprogramming in Atherosclerosis

Advanced Science, EarlyView.
Here we developed Am@SExo, a dual‐functional engineered exosome that coordinates CD47–SIRPα checkpoint blockade with Arg1 mRNA–mediated metabolic reprogramming. Surface SIRPα promotes recognition of apoptotic cells and plaque targeting, while Arg1 expression enhances arginine–ornithine metabolism, Rac1 activation, and actin remodeling in macrophages ...
Danwen Zheng, Shiteng Cai, Jinfeng Gao, Sheng Zhao, Bohan Wei, Xueyi Weng, Zhengmin Wang, Qiaozi Wang, Qiyu Li, Chengzhi Han, Weiyan Li, Yiwen Tan, Yuyuan Fu, Meng Ji, Zheyong Huang, Yanan Song, Juying Qian, Junbo Ge   +17 more
wiley   +1 more source

Targeting Lactate‐Driven Stromal Autophagy via MCT1 Disrupts the Immunosuppressive Niche and Sensitizes Pancreatic Cancer to PD‐1 Blockade

Advanced Science, EarlyView.
Tumor‐derived lactate activates PSCs through MCT1‐mediated Vps34 lactylation and autophagy. These activated PSCs secrete CXCL9/10, upregulating PD‐1 on CD8+ T cells via the CXCR3/STAT3 axis to foster immunosuppression. Disrupting this metabolic crosstalk by targeting MCT1 effectively sensitizes pancreatic cancer to PD‐1 blockade, presenting a promising
Wenfeng Zhuo, Rong Hu, Yuhang Hu, Ping Hu, Shengbo Han, Guozheng Lv, Zhu Zeng, Yong Zhao, Yang Li, Yan Huang, Yingsong Zhao, Hongda Wang, Guangyu Zhao, Eryang Zhao, Gang Zhao   +14 more
wiley   +1 more source

Multiferroic‐Centric Materials and Systems Engineering for Battery Applications: An Insight Into Mechanisms, Strategies, and Characterizations

Advanced Science, EarlyView.
Multiferroic order parameters – polarization, magnetization, and ferroelastic strain – are positioned as dynamic design variables for batteries. Their mechanistic roles, practical tuning through fabrication and external fields, and ferroic‐resolved characterization routes are unified into a closed‐loop framework, revealing how coupled ferroic responses
Jiaqi Su, Yanda Zhu, Hao Peng, Manman Li, Xuzihan Zhang, Meixiao Wu, Siyuan Zhang, Yuhan Zeng, Jiwen Liao, Ming Luo, Hetaishan Huang, Yutong Wang, Sean Li, Wenxian Li   +13 more
wiley   +1 more source

An l-isosorbide-based reactive chiral dopant with high helical twisting power for cholesteric liquid crystal polymers reflecting left-handed circularly polarized light.

Org Chem Front
Dinc RU, Lub J, Kragt AJJ, Schenning APHJ.   +3 more
europepmc   +1 more source

A highly fluorescent bora[6]helicene exhibiting circularly polarized light emission. [PDF]

Chem Sci
Schnitzlein M, Shoyama K, Würthner F.
europepmc   +1 more source

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Photochemistry with Circularly Polarized Light

Angewandte Chemie International Edition in English, 1974
AbstractThe reactions induced by circularly polarized light are reviewed and a general discussion of the induction of optical activity by circularly polarized light is presented. It is concluded that three different mechanisms, or their combinations, can cause asymmetric induction.
Ole Buchardt
exaly   +2 more sources

Circularly Polarized Light‐Driven Supramolecular Chirality

Macromolecular Rapid Communications, 2021
AbstractIntroduction of asymmetry into a supramolecular system via external chiral stimuli can contribute to the understanding of the intriguing homochirality found in nature. Circularly polarized light (CPL) is regarded as a chiral physical force with right‐ or left‐handedness.
Jun Su Kang, Namhee Kim, Taehyung Kim, Myungeun Seo, Byeong‐Su Kim   +4 more
openaire   +3 more sources

Circularly polarized light at the mirror: Caveats and opportunities

Chirality, 2020
AbstractMoving from the simple concept that reflection onto a mirror surface changes the handedness of circularly polarized light, we describe what happens to the emergent polarization in two different cases after reflection on a back mirror. In the first case, a regular emitter is taken into account, where reflection has the effect to destroy the ...
Zinna F., Pescitelli G., Di Bari L.
openaire   +3 more sources

Polarization holography using the circularly polarized light

Imaging and Applied Optics 2014, 2014
The characteristics of the polarization holography of the circularly polarized light are studied based on a tensor theory. The reconstruction wave is disappeared when we use the orthogonal reference wave to reconstruct.
An’an Wu, Jinliang Zang, Ying Liu, Jue Wang, Xiao Lin, Xiaodi Tan, Tsutomu Shimura, Kazuo Kuroda   +7 more
openaire   +1 more source

The effect of circularly polarized light on NMR spectra

Molecular Physics, 1995
Observable shifts in electron spin resonance spectra are predicted to occur as a result of the application of circularly polarized light at a frequency near optical absorption. The shift changes sign with the circularity of the light. In a right circularly polarized beam of intensity 10 W cm −2 and frequency 5 GHz above resonance with the D 1 line ...
A.D. Buckingham, L.C. Parlett
openaire   +1 more source